• Laboratory of Vascular Physiology and Medicine

Section 01

About Us

The vascular system is an extensive network of blood vessels comprising of large conductance vessels and the microcirculation with a remarkable function of distribution and conveyance serving the unique needs of each and every organ right from the subcellular to the cellular levels. With multiple factors making an impact it is challenging to maintain the health and function of the vascular system. The malfunctions of vascular system lead to life threatening conditions like stroke, IHD, atherosclerosis and many more. Among many physiological causes ageing is the most important factor that make serious influence on vascular system. Ageing changes vascular thickness and its elastic recoiling system and alters cardiac hemodynamics. The following factors may be considered as responsible to destabilize vascular physiology:

  • Hereditary background of heart diseases
  • Pregnancy
  • Chronic illness or severe injuries
  • Postural defects
  • Diabetes, thyroid diseases or gonadal hormone abnormalities
  • Smoking
  • Over weight

In this perspective, Department of Physiology under the Faculty of Medicine, BLDE (Deemed to University) established a specialized research laboratory the ‘Laboratory of Vascular Physiology & Medicine’ (LVPM). The Laboratory was formally inaugurated on the 15th December 2015 by Professor Robert G. Carroll (East Carolina University, NC, USA) & Professor Dewan S. A. Majid (Tulane University, New Orleans, USA). This laboratory has been working extensively from molecular to systems covering both areas of Experimental Physiology and Clinical Physiology/Medicine research.

Research Focus

Department of Physiology has established “Laboratory of Vascular Physiology & Medicine” under the supervision of Professor Kusal Das. The laboratory is working extensively on both human and animal model to explore and understand physiological basis of clinical acumen to vascular integrity.

It has a specialized ‘ELECTROPHYSIOLOGY UNIT’, ‘MOLECULAR BIOLOGY UNIT’ and ‘CLINICAL PHYSIOLOGY/MEDICINE UNIT’.

It is also focused to explore vascular function/dysfunction in health and diseased states, with particular emphasis on chronic cardiovascular diseases, diabetes mellitus in addition to vascular responses to exercise and diet and influence of yoga and lifestyle intervention on vascular health. A variety of techniques are utilized to examine macro- and microvascular function as well as arterial stiffness in humans and animal models. Laboratory also devotes itself to carry out different research projects on environmental health, cardiovascular health, respiratory health to functional modulation in different exercise-induced interventional models with their molecular signalling pathways for both human and animal.

Laboratory of Vascular Physiology and Medicine takes care of critical experimental protocol on rats and mice where cardiovascular, vascular, respiratory and neurological different parameters can be analyzed by both non invasive and invasive conditions.

The overall mission of the Laboratory of Vascular Physiology & Medicine is to determine the mechanisms contributing to the development of vascular dysfunction with aging, metabolic syndrome, diabetes, hypertension etc. Our lab uses integrative experimental approaches to assess vascular function of peripheral arteries, stiffness and hemodynamics of the arteries of human.

Objectives

To translate basic science findings with experimental models to clinically relevant applications in humans and testing the efficacy of various pharmacological and lifestyle interventions in humans at high risk for developing cardiovascular diseases.

Vision & Mission

The Laboratory comprises of the faculty members and research scholars who work together in either experimental rodent models or clinical models which primarily focused on cardiovascular problems including hypertension or hypoxia and respiratory diseases. The Laboratory of Vascular Physiology & Medicine is strategically working with its experimental physiologists and clinicians to discover or identify the causes and therapy of vascular diseases including stroke.

The Laboratory which is primarily engaged to understand vascular diseases through their complex mechanisms is also devoted to improve vascular integrity and find out some innovative approaches which may improve the quality of human life or sufferings! The Laboratory is keen to explore multidisciplinary approach through basic scientists, clinical scientists, clinicians, molecular biologists, pharmaceutical chemists, physicists or engineers for understanding & therapeutic aspects of vascular diseases. Laboratory also trains and promotes future researchers in the field of vascular physiology & medicine.

Research Works at LVPM

The Laboratory of Vascular Physiology and Medicine (LVPM) is a multidisciplinary centre dedicated to advancing research in vascular, cardiovascular, respiratory, and neurological health. By integrating clinical physiology, molecular biology, and electrophysiology, the laboratory investigates the mechanisms underlying disease and the effects of interventions at both the human and experimental animal levels.

The laboratory takes care of critical experimental protocol on rats and mice where cardiovascular, vascular, respiratory and neurological different parameters can be analysed by both non-invasive and invasive conditions. LVSM has both invasive and non-invasive rats/mice blood pressure recording transducers. A variety of techniques are utilized to examine macro and microvascular function as well as arterial stiffness in humans and animal models. Both the Clinical Physiology/Medicine & Electrophysiology Unit also devout itself to carry out different research projects on environmental health, cardiovascular health, respiratory health to functional modulation in different exercise induced interventional models with their molecular signalling pathways for both human and animal. LVPM also supports biochemical and basic molecular biology experiments and vascular histopathology which critically analyze arterial wall thickness or lumen diameter in experimental animals. Lab has a sophisticated Molecular Biology Unit where extensive studies on protein expression gene mutation routinely done to understand cell signalling pathways. HIF-1α, NOS3 and VEGF expression in blood and tissues are in the area of molecular biology which this vascular lab is expertise.

The laboratory also devout itself to carry out different research projects on environmental health, cardiovascular health, respiratory health to functional modulation in different exercise induced interventional models like Yoga and life style modulation along with their molecular signalling pathways.

Stroke Model

Translational stroke research is a challenging task that needs long term team work of the stroke research community. Treatment options to date are very limited. To meet the need for novel therapeutic approaches, highly reproducible stroke models with excellent outcome are essential for obtaining useful data from preclinical stroke trials as well as for improving inter-lab comparability. Experimental stroke research frequently employs rodent models of focal cerebral ischaemia. Most researchers use permanent or transient occlusion of the middle cerebral artery (MCA) in mice or rats. Proximal occlusion of the middle cerebral artery (MCA) via the intraluminal suture technique (so called filament or suture model) is probably the most frequently used model in experimental stroke research. The intraluminal MCAO model offers the advantage of inducing reproducible transient or permanent ischaemia of the MCA territory in a relatively non-invasive manner. Intraluminal approaches interrupt the blood flow of the entire territory of this artery. Laboratory of Vascular Physiology & Medicine has established the MCAO technique to induce cerebral ischemia and stroke on rats. The researchers are trained under the supervision of Dr. Sikha Saha, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds. This will further improve to understand focal ischemia/stroke in human and definitely helps to fight against stroke.

Intracerebral haemorrhage (ICH) is the most devastating type of cerebral stroke caused by rupture of intracranial vessels or haemorrhagic transformation of cerebral infarction. LVPM has successfully induced intracerebral haemorrhagic stroke in rodents using autologous blood injection. This technique reliably replicates the pathophysiological features of human haemorrhagic stroke, enabling controlled assessment of neurovascular responses, therapeutic interventions, and recovery mechanisms. The successful induction and standardization of this model underscore the laboratory’s advanced experimental capabilities and commitment to high-quality preclinical research.

Figure 1: Scheme of the procedure of acute hemorrhagic stroke in the capsula interna of Wistar rats. The red line and the red triangular area correspond to the post-surgery location of the damage. C.i. — Capsula Interna.
Figure 1: Scheme of the procedure of acute hemorrhagic stroke in the capsula interna of Wistar rats. The red line and the red triangular area correspond to the post-surgery location of the damage. C.i. — Capsula Interna.
Figure 1: Scheme of the procedure of acute hemorrhagic stroke in the capsula interna of Wistar rats. The red line and the red triangular area correspond to the post-surgery location of the damage. C.i. — Capsula Interna.
Figure 1: Scheme of the procedure of acute hemorrhagic stroke in the capsula interna of Wistar rats. The red line and the red triangular area correspond to the post-surgery location of the damage. C.i. — Capsula Interna.

Section 02

People

Mentor

Kusal K. DasPhD; FRSB

Distinguished Professor of Physiology

Shri B. M. Patil Medical College, Hospital & Research Centre,

BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

kusaldas@bldedu.ac.in

Faculty in charge

Dr Shrilaxmi BagaliMD; PhD

Assistant Director and Co-ordinator

Laboratory of Vascular Physiology and Medicine, Department of Physiology,

Shri B M Patil Medical College, Hospital & RC, BLDE (Deemed to be University), Vijayapura – 586103, Karnataka, India.

shrilaxmi.bagali@bldedu.ac.in

Research Faculty

Ishwar B. BagojiPhD

Associate Professor of Anatomy

Shri B. M. Patil Medical College, Hospital & Research Centre, BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Gouher Banu ShaikhMD; PhD

Associate Professor of Physiology

Shri B. M. Patil Medical College, Hospital & Research Centre, BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Lata MullurMD; PhD

Professor of Physiology

Shri B. M. Patil Medical College, Hospital & Research Centre, BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Jyoti KhodnapurMD; PhD

Professor of Physiology

Shri B. M. Patil Medical College, Hospital & Research Centre, BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Anita TeliMD; BLSM

Life Style Medicine Physician, Associate Professor of Physiology

Shri B. M. Patil Medical College, Hospital & Research Centre, BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Prachi ParvatikarPhD

Assistant Professor, Science and Technology

BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Supriya BhosalePhD

Assistant Professor, Science and Technology

BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Junior Research Fellow

Shweta Rani

BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Ali Javed Akki

Science and Technology, BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Vijayalaxmi Patil

Science and Technology, BLDE (Deemed to be University), Vijayapura-586103, Karnataka, India.

Section 03

Brief Scientific Profile of Prof. Kusal K Das — Mentor

Prof. Das did his PhD in Physiology from University of Calcutta and his thesis was entitled "Metallic Pollution: It’s effect on male reproductive system with special references to protein inadequacy". His earlier research works basically on heavy metal toxicities and how these metals especially divalent cation alters system biology. His research established a link between nutritional role especially dietary protein and severity of impaired functional biology including reproductive health in experimental animals. Professor Das exclusively worked on changes in DNA, RNA and genetic information systems due to heavy metal assaults in albino rats in relation to dietary proteins and antioxidant vitamins particularly Vitamin C and E (Das & Das gupta 1997; Das & Das gupta 2000; Das & Das gupta 2002). His works on vitamin C and E against nickel, Cr VI and Pb treated pathophysiology of cardiovascular, renal, pulmonary, reproductive and hepato-biliary system are noteworthy (Gupta 2008; Das 2015). His works also showed an elevation of serum glucose level in rats supplemented with megadose of vitamin C as l-ascorbic acid. Further of his research extended to human occupational exposure on heavy metals especially on lead (Pb) and oxidative stress though NF-kβ (Das et al 2011; Chadchan et al 2014; Mantur et al 2014; Das et al 2016; Das et al 2017, Reddy et al 2020; Das et al 2020).

Prof. Das’s research on experimental biology further progress on low oxygen microenvironment in rodents especially in chronic sustained and intermittent hypoxia in experimental animals treated with heavy metals (Nickel and Lead). He has published series of his research works on cell signal transduction in hypoxia exposed animals though identification of hypoxia sensitive genes like hypoxia-inducible factor-1α (HIF-1α), erythropoietin (Epo) and vascular endothelial growth factor (VEGF) expressions in presence of divalent cation metals (Das et al 2015; Hattiwale et al 2013). Further he has done extensive research on the regulation of vascular endothelial and smooth muscle integrity though NOS3/NOS2 gene expression in hypoxia exposed rodents (Patil et al 2015; Das and Saha 2014). One of his works on hypoxia, divalent heavy metals and glucose intolerance in rodents showed the definite involvement of L/N type of calcium channel and cardiac autonomic dysfunctions with both chronic sustained and intermittent hypoxia. This work suggests a possible therapeutic uses of L/N type of calcium channel blockers to control hypoxia or metal induced hyperglycemia. He is also engaged in research on ageing related oxygen sensing gene and vascular physiology relationship especially on arterial stiffness including augmented index in human (Das et al 2017; Das et al 2016; Das et al 2019).

Professor Das invented a new modified method of estimation of serum Vitamin E (α-tocopherol) which is economic, less tedious and less time consuming (Jargar et al 2012). This invention made him to get The Physiological Society, UK scholarship to University of Edinburgh.

Currently Prof. Das is working on isolation of specific bioactive compounds from some indigenous plants of north Karnataka and synthesizing analogues of these bioactive compounds to develop a drug against ‘stroke’. His laboratory is using in vivo, in vitro and in silico model to develop drugs against neurovascular disorders. He has active research collaboration with Tulane University, USA, University of Leeds, UK, IIT-Kanpur and NIPER-Hyderabad. Dr. Das’s laboratory established the complex technique of rodent stroke model by middle cerebral artery occlusion (MCAO) technique. Prof. Das also contributed a lot in environmental biology especially on ground water arsenic and fluoride contamination in north Karnataka, India. He is one of the first to describe overt arsenicosis in such an area as well as in this region of Karnataka, India. For his work he has been conferred “Dr. Raja Ramanna State Scientist 2015” by Government of Karnataka, India and “G.P. Chatterjee Memorial Award 2019” by Indian Science Congress Association, Ministry of Science & Technology, Government of India. Prof. Das is a Fellow of Royal Society of Biology, UK.

Prof. Das has been awarded with state award (Rajya Prashasti) by Government of Karnataka (2023) for contribution in Science & Technology as a person with disability. For his contribution towards physiological sciences, Prof Das has been honoured with ‘Life Time Achievement Award’ (2025) by South Asian Association of Physiologists, University of Colombo, Sri Lanka. He was awarded ‘Plurinational Science and Technology Award’ by Ministry of Education, Republic of Bolivia (2021).

Prof. Das has been consistently recognized by Stanford University’s World Top 2% most influential scientists (Health Sciences) for three consecutive years 2023, 2024 and 2025.

Section 04

Research Models Developed at Vascular Laboratory

Chronic sustained hypoxia model (10% Oxygen; 90% N2)
Rodent stroke model by middle cerebral artery occlusion (MCAO) technique
Rodent haemorrhagic stroke model
Protein restricted dietary model (5% Casein)
Hyperlipidemia dietary model in rats (30% fat)
Salt sensitive hypertensive (SSH) models by inducing L-NAME & NaCl
Renal arterial occlusion model for developing renal hypertension
In Silico Drug Development Model

Section 05

Core Facilities

A. Electrophysiology

1. MP45 Biopac Student Lab

  • Rat & Human ECG Monitoring
  • Pneumogram
  • HRV Analysis
  • Animal (Rat/mice) invasive Blood Pressure Monitoring
  • Animal (Rat/mice) non-invasive Blood Pressure Monitoring
  • EEG and other neurological works
  • EMG etc. on both rats & human

Electrophysiology Unit of Laboratory of Vascular Physiology and Medicine

2. Small animal Radio telemetry system

  • Pressure telemetry foundation system
  • Biopotential telemetry system with lab chart pro analysis software

Periscope: It is an automated cardiovascular analyzer. It analyzes arterial stiffness, estimates simultaneous four limb blood pressure, central aortic blood pressure and cardiac indices from pressure analysis.

Electrophysiology recording setup at LVPM — invasive blood pressure measurement through transducer (Biopac MP 45)
Electrophysiology recording setup at LVPM — invasive blood pressure measurement through transducer (Biopac MP 45)

B. Hypoxia Chamber

Hypoxia chamber (BIOXIA, H800) at Laboratory of Vascular Physiology and Medicine, Department of Physiology.

The hypoxia chamber is a controlled environment system designed to simulate hypoxic conditions for in vivo and in vitro experiments. It allows precise regulation of oxygen, carbon dioxide, humidity, and temperature levels, making it ideal for studying cellular and physiological responses to hypoxia in animal models such as albino Wistar rats. This instrument is crucial for research in pulmonary hypertension, ischemia, and other hypoxia-related pathologies.

Hypoxia chamber (BIOXIA, H800) at Laboratory of Vascular Physiology and Medicine
Hypoxia chamber (BIOXIA, H800) at Laboratory of Vascular Physiology and Medicine
Gas supply for the hypoxia chamber workstation (10% Oxygen; 90% N2)
Gas supply for the hypoxia chamber workstation (10% Oxygen; 90% N2)

C. Molecular Biology

1.ELISA Micro-plate Reader

Qualitative & Quantitative analysis of the Biologically important compounds (Hormones, Growth factors, Specific Bacterial or Viral Antigens) based on their Immune property. (eg: VEGF, HIF 1 alpha, etc)

2.ELISA Micro-plate Washer

It is used in the process of washing the microplates to remove the excess/unbound antigens/antibodies with specific Buffer where we can set the Number of washing cycles.

3.Western Blotting Apparatus (BIO RAD, Chemidoc XRS +)

To evaluate Protein expressions in blood & tissues

4.PCR machine (T100 Thermal cycler, BIO RAD)

To identify the specific gene for gene mutation studies by using restriction fragment length polymorphism (RFLP) technique

5.Cold Centrifuge (–20°C with 20000 rpm, REMI)

6.Vertical Deep Freezer (ELANPRO –20°C)

7.Digital pH meter (Global DPH 500)

8.Centrifuge (REMI R-4C)

9.Water bath (BR BIOCHEM LIFE SCIENCES)

10.Electronic Balance

11.Tissue Homogenizer (REMI)

Western Blotting Apparatus
Western Blotting Apparatus
Western Blotting Apparatus
Western Blotting Apparatus

D. Clinical Biochemistry

UV Visible Spectrophotometer (Shimadzu UV 1800)

  • Qualitative & Quantitative analysis of Biologically important compounds.
  • Enzyme kinetics
  • To Study the absorption Spectra of compounds
  • Quantitative analysis of pharmaceutical substances

E. Bioinformatics work station (Cresset Flare — pro plus)

Cresset Flare Pro Plus is an advanced molecular modelling and drug discovery software used for structure-based design, ligand-based design, and molecular docking. It enables visualization of protein–ligand interactions, pharmacophore modelling, electrostatics analysis, and SAR interpretation, facilitating efficient lead optimization.

Bioinformatics / Computational Biology

  • Drug screening (ADME)
  • Molecular Docking
Bioinformatics workstation at LVPM with a 3D protein model on screen
Bioinformatics workstation at LVPM with a 3D protein model on screen

Applications — Western blotting system

Western blotting is a widely used technique for the detection and analysis of proteins. It is frequently used to study single proteins but the advent of multiplexed, fluorescence-based detection enables the simultaneous detection of several proteins. Western blotting, or immunoblotting, is used for both qualitative and quantitative analysis of protein expression in a wide variety of biological samples.

  1. 01Western blot is applied in a confirmatory HIV-test to detect anti-HIV antibody in a human serum sample. Proteins like gp41, gp120, from known HIV-infected cells are separated and blotted on a membrane.
  2. 02Under appropriate conditions, the western immunoblotting technique is quantitative. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) separated viral proteins.
  3. 03Medical diagnosis application of western blot is a confirmatory test for Hepatitis B and C Viral infection.
  4. 04It can be used to find out Cancer gene transcriptional factors expression as proteins.
  5. 05It can be used to find out vascular gene expression as proteins.
  6. 06Western blotting is useful in the salivary diagnosis of Helicobacter pylori infection.
  7. 07Application of electrophoresis and western blot to detect IgG in CSF of patients with multiple sclerosis.

Applications — PCR

A thermal cycler (also called thermocycler) is an instrument that employs precise temperature control and rapid temperature changes to conduct the polymerase chain reaction (PCR). PCR is used to create billions of copies of a DNA sequence for use in a wide array of downstream procedures including cloning, sequencing, expression analysis, and genotyping.

  1. 01For the amplification of genomic DNA
  2. 02For gene mutation studies by using restriction fragment length polymorphism (RFLP) technique
  3. 03To make copies of gene of interest for cloning
  4. 04For qualitative gene identification (presence or absence of specific gene)

Section 06

Funded Projects

Extramural Funding — Ongoing

CCRH, Ministry of Ayush, Government of India, New Delhi.

Homeopathic formulation of Crotalus Horridus venom for the therapeutic reduction of vascular permeability in haemorrhagic stroke as found in dengue fever.

Fund: Rs. 40,66,748.00/-

Project sanctioned No. Ref: F.No.17-47/2023-24/CCRH/Tech./Coll./BLDE University/1395-1400; Dtd 28-08-2024 (email dtd. 02-09-2024).

VGST-K FIST (Level 2), DST, Government of Karnataka (sanctioned 2023).

Wnt/β-catenin signalling in hypoxia-induced pulmonary hypertension – Role of bioactive molecule of Mucuna pruriens.

Fund: Rs. 20,00,000.00

vide K-FIST L2/GRD No. 1030/2021-22/440 dated 15.02.2023.

ANRF, Science and Engineering Research Board, DST, Govt. of India

Effect of bioactive compounds of Terminalia arjuna on gene expression profile and biomarkers of extracellular vesicles in liver diseases.

Fund: Rs. 18,30,000.00

Diary No. ANRF/F/1221/2024-2025

VGST-K FIST (Level 2), DST, Government of Karnataka

Identification of anti-cancer activities of isolated bioactive compounds from Terminalia arjuna on MicroRNA Expression Profiles on Hepatocellular Carcinoma Cells.

Fund: Rs. 20,00,000.00

Extramural Funding — Completed

LSRB, DRDO, Ministry of Defence, Government of India (2014–2017, extended 2019 September).

Influence of antioxidant vitamin (L-ascorbic acid) on hypoxia-induced alteration of VEGF gene expression in male diabetic rats with or without exposure to heavy metal nickel.

Fund: Rs. 27,40,600/-

Vide Sanction letter: No O/o CC R&D(TM)/81/48222/LSRB-XXIX-Meeting/2014, 06th August 2014 [Completed]

VGST-K FIST (Level 2), DST, Government of Karnataka (2016–2019).

Effect of L-ascorbic acid and calcium channel blocker on hypoxia exposed possible alteration of cell signalling pathways in respiratory system of male rats with or without heavy metal lead exposure.

Fund: Rs. 40,00,000/-

VGST-KFIST/1230/2015 Dated 22/6/2016 [Completed]

BLDE (DU) funded projects — Ongoing

Cardiac specific miRNA signature in low oxygen microenvironment: Role of cilnidipine, a dual L/N type calcium channel blocker.

Fund: Rs. 2,65,000/-

BLDE (DU) funded projects — Completed

Neuroprotective effect of bioactive compound from Mucuna pruriens (velvette bean) by in silico, in vivo approaches

Fund: Rs. 1,50,000.00, 2 publications

Effect of cilnidipine in two forms (L-NAME and L-NAME+4% NaCl) of hypertensive rats

Fund: 2023, Rs. 3,10,000, 3 publications, 1 copyright

Wnt/β catenin signalling on hypoxia induced pulmonary artery smooth muscle cell proliferation and role of bioactive molecule of Mucuna pruriens

Fund: 2025, 2 publications and 1 copyright

Association of dietary patterns with inflammatory biomarkers, oxidative stress and endothelial function

Fund: 2023, Rs. 25,000, 1 publication

Effect of cilnidipine on brain pathophysiology in two forms (L-NAME and L-NAME+4% NaCl) of hypertensive rats

Fund: 2025

Section 07

Student Training — Academic and Research Engagement

ICMR STS Projects — Ongoing

Reference ID: STS 2024-02038

Assessment of cognitive functions and arterial stiffness in patients with anaemia

Student: Ms Aseema Anakal · Guide: Dr Shrilaxmi Bagali

Reference ID: STS 2025-14412

Diabetes Risk Assessment in Young Adults using Indian Diabetes Risk Score and its Association with Vascular Stiffness

Student: Ms Trisshala Chandrashekhar Devlapalli · Guide: Dr Shrilaxmi Bagali

Post Graduate Research Project

Role of Micro RNA-765 on Vascular Pathophysiology in Hypertensive Subjects

PG student: Dr Akanksha Singh · Guide: Dr Shrilaxmi Bagali

External Student Training Programs

Ms. Ashmita Acharya, 1st year BS-MS Program, Indian Institute of Science and Education Research, Tirupati (IISER Tirupati), underwent one month training under summer internship program from June 3rd 2024 to July 2nd 2024. The training included Basic Neurosciences (Neuroanatomy, Neurophysiology and Neurogenetics, Molecular Biology, Basics of Bioinformatics) and Clinical Neurosciences (Neuropathology and Neurosurgery). The student also made a presentation on Effects of Chimerism on Neurophysiology.

Ms. Ashmita Acharya, 1st year BS-MS Program, IISER Tirupati
Ms. Ashmita Acharya, 1st year BS-MS Program, IISER Tirupati
Ms. Ashmita Acharya, 1st year BS-MS Program, IISER Tirupati and Dr Lata Mullur, HOD, Physiology
Ms. Ashmita Acharya, 1st year BS-MS Program, IISER Tirupati and Dr Lata Mullur, HOD, Physiology

Section 08

Moments with Our Distinguished Guests

Guests from University of Sao Paulo at LVPM
Guests from University of Sao Paulo at LVPM
Guests from University of Sao Paulo at LVPM
Guests from University of Sao Paulo at LVPM
Guests from University of Sao Paulo at LVPM
Guests from University of Sao Paulo at LVPM

Prof Benedito Machado, Prof and Advisor, Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil and Prof. Lusiane M. Bendhack, Former Professor of Pharmaceutical Chemistry, University of Sao Paulo, Sao Paulo, Brazil at LVPM, Oct 6–9, 2025.

CCRH, New Delhi team visit to LVPM
CCRH, New Delhi team visit to LVPM
CCRH, New Delhi team visit to LVPM
CCRH, New Delhi team visit to LVPM

Visit by Central Council for Research in Homeopathy (CCRH, New Delhi) team to LVPM, 3rd July 2024.

Interaction with eminent Prof of Medicine Prof Dr P. S. Shankar at LVPM, 20th May 2023
Interaction with eminent Prof of Medicine Prof Dr P. S. Shankar at LVPM, 20th May 2023
Visit by Prof. Nanduri Prabhakar, University of Chicago, 19th Dec 2022
Visit by Prof. Nanduri Prabhakar, University of Chicago, 19th Dec 2022

Visit by Prof. Nanduri Prabhakar, Harold H Hines Endowed Professor of Medicine & Director, Centre for Systems Biology & Oxygen sensing, Department of Medicine, University of Chicago, Chicago, IL-60637 & Invitee, Nobel Institute for Physiology & Pharmacology, Stockholm, Sweden, 19th Dec 2022.

Section 09

International Recognition

  • Prof. Kusal K Das was recognized as Stanford University’s World Top 2% most influential scientists (Health Sciences) for 2023, 2024 and 2025.
  • Prof. Kusal K Das is Dean & Interregional Coordinator, Department of Environmental Health, UNESCO Chair-Life Sciences (Biophysics, Biotechnology & Environmental Health), LSIPEC, Yerevan, Armenia (August 1, 2020 – December 31, 2026).
  • Laboratory of Vascular Physiology is a part of UNESCO/UNITWIN Network affiliated laboratory under UNESCO Chair-Life Sciences (Biophysics, Biotechnology and Environmental Health). This centre is the coordinator of Environmental Health under UNESCO Chair Life Sciences.

Section 10

Awards & Honors

  1. 01Prof. Kusal Das was conferred Life Time Achievement Award (2025) by South Asian Association of Physiologists, University of Colombo, Sri Lanka.
  2. 02Prof. Kusal K Das was conferred State award (Rajya Prashasti) – 2023 for contribution in Science & Technology as a person with disability, Government of Karnataka.
  3. 03Prof. Kusal K Das received Plurinational Science and Technology Award 2021, awarded by Ministry of Education, Republic of Bolivia.
  4. 04Prof. Kusal K Das was conferred with Founder Fellow, The Physiological Society of India, 2021.
  5. 05Prof. Kusal Das is an Honorary Fellow, KSTA, DST, Government of Karnataka 2021.
  6. 06Dr Lata Mullur is the Vice-President, Physiological Society of India, 2023-25.
  7. 07Dr Shrilaxmi Bagali received Bharat Gaurav Puraskar from KTK outstanding achievers and education foundation, New Delhi.
  8. 08Dr Anita Teli received Bharat Gaurav Puraskar from KTK outstanding achievers and education foundation, New Delhi.

Honors & Awards in detail

Prof. Kusal K. Das

Prof. Kusal Das is receiving ‘G.P. Chatterjee Memorial Prize’ from Indian Science Congress Association, Ministry of Sc. & Tech., Government of India in Jalandhar, Punjab on January 3, 2029. Prof. Das is receiving “Dr. Raja Ramanna State Scientist Award 2015” by KSCST, Government of Karnataka.

  • 2019 – “G.P. Chatterjee Memorial Award 2019” by ISCA, DST, Ministry of Science & Technology, Government of India on January 3, 2019
  • 2018 – “Silver Jubilee Oration 2018” by KIMS Deemed to be University, Karad, Maharashtra on 6th March 2018
  • 2018 – Fellow of Royal Society of Biology (United Kingdom) by The Royal Society of Biology, London
  • 2017 – “Dr. Jajneswar Chakraborty Memorial Oration 2017” by Bengal Obstetrics & Gynecological Society, Kolkata (July 8, 2017)
  • 2016 – Science, Honor and Truth Medal by IIPH-Zubieta University, La Paz, Bolivia
  • 2016 – Shri S. N. Chaudary Memorial Research Prize by Association of Physiologists of India, JIPMER
  • 2015 – Dr. Raja Ramanna State Scientist Award 2013 by Ministry of Science & Technology, Government of Karnataka on 30th Dec 2015
  • 2015 – MCRC-Research Lecture by Multidisciplinary Cardiovascular Research Centre, the University of Leeds on 31st July 2015

Dr. Shrilaxmi Bagali

  • SARS Gold Medal by SARS, Shri B. M. Patil Medical College, Vijayapur for best research paper presentation 2018
  • Research Day Medal by BLDE (Deemed to be University) in Faculty category on June 6, 2018
  • 1st Prize for best research presentation on Research Day Celebration 2019 at BLDEA’s College of Engineering and Technology, Vijayapur during May 2019
  • Young Scientist Award 2019 by BLDE (Deemed to be University), 2019

Dr. Lata Mullur

  • Research Day Medal (Poster) by BLDE (Deemed to be University) in PhD Scholar category on June 6, 2018

Jyoti Khodnapur

  • SARS Gold Medal by SARS, Shri B. M. Patil Medical College, Vijayapur for best research paper presentation 2017
  • 2019 – Received “BEST PAPER AWARD” and First prize for paper presentation in DIACON 2019
  • 2016 – Received “BEST PAPER AWARD” at 3rd Annual conference of Association of Physiologists of India, ASSOPICON 2016, during 14th to 17th September 2016 held at Department of Physiology, BLDE University’s Shri B. M. Patil Medical College and Research Centre, Vijayapur
  • 2014-2018 – University Research fund to pursue PhD in Physiology

Ishwar B. Bagoji

  • Young Scientist Award 2017 by BLDE (Deemed to be University) during convocation, September 2017

UNESCO / UNITWIN Network under UNESCO Chair — Life Sciences

  • UNESCO/UNITWIN Network under UNESCO Chair-Life Sciences: Laboratory of Vascular Physiology and Medicine becomes the Coordinating centre for training PhD students in Environmental Health research. This Interregional network on PhD Education and Research in Biophysics, Biotechnology and Environmental Health is under UNESCO Chair Life Sciences. Prof. Kusal K. Das is appointed as Coordinator for Environmental Health (2019-2024). Link: http://www.biophys.am/pages/index/About-the-Network
  • Under UNESCO Chair Life Sciences BLDE (Deemed to be University), India, Professor Kusal Das is also appointed as UNESCO COVID-19 Weekly Skype Meeting in March 2020.
  • In one of the weekly UNESCO COVID-19 Skype meetings which is coordinated by LVPM, BLDE (Deemed to be University), 17 countries with 37 participants – doctors/scientists around the world – discussed in more than 10 meetings from March 2020 to June 2020. The program is chaired by UNESCO Chair Life Sciences Prof. Sinerik Ayrapetyan (Armenia). For details: http://www.biophys.am/pages/view/266

Section 11

Publications

Research Publications (2021–2025) — 43 entries

  1. 1.Akki AJ, Nanduri S, Patil SV, Das KK, Parvatikar P. Exploring the microRNA-mitochondrial nexus in hepatocellular carcinoma. Mitochondrion 2025, 84: 102045. DOI: 10.1016/j.mito.2025.102045 (IF: 3.9)
  2. 2.Dhange M, Salgare S, Das Kusal K. et al. Hemodynamic properties of blood flow in an angled overlying stenosed blood vessel via force field and gold nanoparticle suspension. Scientific African, 2025; 28: 10.1016/j.sciaf.2025.e02652. (IF 2.7)
  3. 3.Banu Shaikh G, Das K K. Cilnidipine: An L- and N-Type Blocker of Calcium Channels Ameliorating Renal Damage in Experimental Hypertensive Rats. Cureus 2025; 17(3): e81404. DOI 10.7759/cureus.81404
  4. 4.Dhange M, Sankad G, Bhujakkanavar U, Das KK, Misra JC. Hemodynamic characteristics of blood flow in an inclined overlapped stenosed arterial section. Partial Differential Equations in Applied Mathematics, 2024, 11, 100829
  5. 5.Bagali S, Kanthe P, Reddy RC, Patil S, Das KK. Hypoxia-Induced Impairment of Glucose Homeostasis: Sympathovagal Imbalance and the Potential Therapeutic Role of L/N type Calcium Channel Blocker Cilnidipine; Physiology Pharmacol (Iran) 2024; 28(3): 304–313
  6. 6.Yendigeri SM, Arakeri SU, Das KK. Effect of 1,25-Dihydroxy Vitamin D3 (1,25(OH)2 D3) Supplementation on Hexavalent Chromium [Cr(VI)]-Induced Hepatoxicities in Male Albino Rats. Med J Dr. DY Patil Vidyapeeth 2024, 17: S186-S192
  7. 7.Bhosale S, Bagali S, Parvatikar PP, Das KK. Effect of bioactive compounds of Mucuna pruriens on proteins of Wnt/β catenin pathway in pulmonary hypertension by in silico approach. In Silico Pharmacol. 2024 Nov 19;12(2):110. doi: 10.1007/s40203-024-00263-8
  8. 8.Page M, Bagali S, Das KK. Comparison of Biomarkers of Oxidative Stress, Inflammation, and Endothelial Function Among Vegetarians and Non-vegetarians of Vijayapura, India: A Pilot Study. Cureus. 2024 Aug 31;16(8):e68342. doi: 10.7759/cureus.68342 (IF 1.2)
  9. 9.Patil SM, Khodnapur J, Das KK, Poddar A. The Role of Serum Erythropoietin (EPO) and Vascular Endothelial Growth Factor (VEGF) in Pulse Wave Velocity (PWV) Among Hypertensive Patients: A Cross-Sectional Study. Cureus 16(6): e62416. DOI 10.7759/cureus.62416 (IF 1.2)
  10. 10.Bhosle S, Bagali S, Parvatikar PP, Das KK. Physiochemical extraction, screening, and antimicrobial in vitro free radical scavenging activity of plant Mucuna pruriens. Afr J Biol Sci 2024; 6(5): 6450-6460.
  11. 11.Terdale AB, Unki SN, Ganesh PS, Das KK, Das SN. Development of a Diethylcarbamazine Citrate-Based Electrochemical Sensor for Quick and Affordable Detection of Sulfadiazine and Uric Acid in Environmental Monitoring. Chemistry Select 2024; 9, e202401047. doi.org/10.1002/slct.202401047 (IF 2.1) (Q2)
  12. 12.Patel S, Parvatikar P, Bhosle S, Patil SM, Das KK. Repurposing of potential bioactive compounds from various database to study their effects on MMP-7 by virtual screening. Res J Biotech 2024; 19(2):14-19. DOI: 10.25303/1902rjbt014019
  13. 13.Das SK, Nerune SM, Das KK. Antioxidant therapy for hepatic diseases: a double-edged sword. J Basic Clin Physiol Pharmacol. 2024 Jan 19. doi: 10.1515/jbcpp-2023-0156
  14. 14.Das KK. Graduate medical education: variation of program and training duration. Korean J Med Educ. 2023;35(4):417-419. DOI: https://doi.org/10.3946/kjme.2023.277 (Q2)
  15. 15.Das KK, Carroll RG. Ethical teaching for physiology educators. Indian J Physiol Pharmacol 2023;67:237-8 (Q4)
  16. 16.Das KK, Majid DSA, Prabhakar NR. Editorial: Vascular pathophysiology in hypoxia. Front. Physiol. 2023; 14:1235383. doi: 10.3389/fphys.2023.1235383 (IF 4.2) (Q1)
  17. 17.Patel SK, Aithala M, Patil S, Das KK. β-sitosterol on heart rate variability in L-NAME induced hypertensive rats. J Krishna Inst Med Sci Univ 2023, 12(1): 97-106 (Q4)
  18. 18.Hegde R, Hegde S, Kulkarni SS, Das KK, Gai PB. Glutathione S Transferase Theta1 and Mu1 (GSTT1 and GSTM1) deletion among autistic population of India. Current Psychiatry Research and Reviews 2023; doi: https://dx.doi.org/10.2174/2666082219666230302142608 (Q4)
  19. 19.Parvatikar P, Bagali S, Hippargi S, Singh PK, Singh SB, Biradar MS, Patil AV, Das KK. Identification of Potent Bioactive Molecules against NMDA Receptor and Tau Protein by Molecular Docking Approach. Letters in Drug Design & Discovery 2023; 20; 1031-1033. https://dx.doi.org/10.2174/1570180819666220616142153 (IF 1.0) (Q2)
  20. 20.Parvatikar PP, Patil SM, Patil BS, Reddy RC, Bagoji I, Kotennavar MS, Patil S, Patil AV, Das KK, Das SN and Bagali S (2023), Effect of Mucuna pruriens on brain NMDA receptor and tau protein gene expression in cerebral ischemic rats. Front. Physiol. 2023. 14:1092032. doi: 10.3389/fphys.2023.1092032 (IF 4.2) (Q1)
  21. 21.Honutagi RM, Sunil R, Patil SM, Bhosale S, Das SN, Parvatikar PP, Das KK. Protein-protein interaction of LDH and CRP-1 with hematotoxin snake venom proteins of all species of snake: An in silico approach. Int J Health Sci (Qassim). 2023 Mar-Apr;17(2):10-15 (Q3)
  22. 22.Hegde R, Hegde S, Kulkarni S, Kulkarni SS, Pandurangi A, Kariduraganavar MY, Das KK, Gai PB. Total Reflection X-ray Fluorescence Analysis of Plasma Elements in Autistic Children from India. Biol Trace Elem Res. 2023 Feb;201(2):644-654. doi: 10.1007/s12011-022-03199-2 (IF 3.9) (Q1)
  23. 23.Das KK. Vascular physiology: A bridge between health and disease. Indian J Physiol Pharmacol 2022; 66:155-6. doi:10.25259/IJPP_414_2022 (Q4)
  24. 24.Patil Vidya A, R Prasad Saikrishna, L. K Shivanand, Holyachi Renuka, Das Kusal K*, T. K. Vijaykumar. Efficacy of BAINS circuit in treating critically ill hypoxemic COVID-19 patients during second wave of pandemic in India. Reviews on Recent Clinical Trials 2022; 17(2); 86-91. (Q3) https://dx.doi.org/10.2174/1574887117666220308093306
  25. 25.Patel SK, Shutter AK, Patil R, Desangi A, Malali V, Patil J, Patil S, Das KK, Parvatikar PP. In-Vitro Antioxidant, Anti-Inflammatory and Cytotoxic effects of different Solvent Extraction Terminalia chebula, Terminalia bellirica, Phyllanthus emblica. Research J. Pharm. and Tech 2022; 15(7): DOI: 10.52711/0974-360X.2022.00490 (Q3)
  26. 26.Herur A, Aithala M, Das KK, Mallapur A, Hegde R, Kulkarni S. Interplay of Oxidative Stress and Nitric Oxide Synthase Gene Expression on Cardiovascular Responses in Preeclampsia. Rev Bras Ginecol Obstet. 2022 Jan 31. doi: 10.1055/s-0042-1742313. PMID: 35100630 (Q3)
  27. 27.Hegde S, Hegde R, Kulkarni SS, Das KK, Gai PB. Analysis of Genetic Variations in Connexin 26 (GJB2) Gene among Nonsyndromic Hearing Impairment: Familial Study. Glob Med Genet 2022; DOI https://doi.org/10.1055/s-0042-1743257
  28. 28.Parvatikar P, Saha B, Das SK, Reddy RC, Bagali S, Kulkarni RV, Patil AV, Biradar MS, Das KK. Molecular Docking Identifies Novel Phytochemical Inhibitors Against SARS-COV-2 for Covid-19 Therapy. Research J. Pharm. and Tech 2022; 15(2):555-558 (Q3)
  29. 29.Kulkarni S, Hegde R, Hegde S, Kulkarni SS, Hanagvadi S, Das KK, Kolagi S, Gai PB, Bulagouda RS. Clinical profile of hemophilia B patients from Karnataka. J Family Med Prim Care. 2022 Jun;11(6):2735-2738. doi: 10.4103/jfmpc.jfmpc_1773_21
  30. 30.Hegde R, Hegde S, Kulkarni SS, Pandurangi A, Das KK, Gai PB. Human homeostatic iron regulator gene polymorphism in autistic population of India; a case-control study. Gene Reports 2022; 26: 101518. https://doi.org/10.1016/j.genrep.2022.101518 (Q4)
  31. 31.Parvatikar PP, Patil S, Hosker J, Swargam S, Kulkarni RV, Das KK. Screening and Development of Transglutaminase-2 Inhibitors and their Derivative as Anti-lung Cancer Agent by in silico and in vitro Approaches. Current Computer-Aided Drug Design 2022; 18: 41-51. https://doi.org/10.2174/1573409917666210322120350 (IF 1.7) (Q3)
  32. 32.Shaikh GB, Hippargi S, Majid DSA, Das KK. Protective actions of cilnidipine: Dual L/N type calcium channel blocker against hypertensive renal injury in rats. Biomed Pharmacol J 2021; 14(4): 1887-1893
  33. 33.Herur A, Aithala MR, Das KK, Mallapur A. Autonomic functions in pre-eclampsia and normal pregnancy. Teikyo Med J 2021; 44(3): 762-767.
  34. 34.Hegde R, Hegde S, Kulkarni SS, Pandurangi A, Gai PB, Das KK. Genetic Analysis of Neuroligin 4Y Gene in Autism Population of India. Global Medical Genetics 2021; 10.1055/s-0041-173623
  35. 35.Hegde R, Hegde S, Kulkarni SS, Pandurangi A, Gai PB, Das KK. Genetic analysis of the postsynaptic transmembrane X-linked neuroligin 3 gene in autism. Genomics Inform 2021;19(4):e50; https://doi.org/10.5808/gi.21029 (Q2)
  36. 36.Mantur VS, Somannavar MS, Hegde S, Vernekar S, Das KK, Goudar SS. Black tea extract ameliorates pancreatic dysfunction in male Wistar rats exposed to cadmium chloride. Pravara Med Rev 2021; 13(03):31-36. (Q4)
  37. 37.Kulkarni SS, Hanagvadi S, Das KK, Kolagi S, Gai PB, Rudragouda. Mutation analysis and characterisation of F9 gene in Haemophilia-B population of India. Blood Research 2021; doi:10.5045/br.2021.2021016 (IF 1.65) (Q3)
  38. 38.Khodnapur JP, Das KK. Age-associated changes in vascular health and its relation with erythropoietin. Indian J Physiol Pharmacol 2021;65(2):119-26. (Q4)
  39. 39.Hegde R, Hegde S, Kulkarni SS, Pandurangi A, Gai PB and Das KK. Novel frameshift mutation in Indian autistic population causes neuroligin and neurexin binding defect. Gene Reports [Elsevier] 2021; 24: https://doi.org/10.1016/j.genrep.2021.101245 (Q4)
  40. 40.Kanthe PS, Patil BS, Das KK, Parvatikar PP. Structural analysis and prediction of potent bioactive molecule for eNOS protein through molecular docking. In Silico Pharmacol. 2021; 9: 48. https://doi.org/10.1007/s40203-021-00106-w
  41. 41.Hegde S, Hegde R, Kulkarni SS, Das KK, Gai PB, Bulgouda R. Molecular alteration in the Gap Junction Beta 2 (GJB2) gene associated with non-syndromic sensorineural hearing impairment. Intractable and Rare Diseases Research 2021; 10: 31-3 (Q3)
  42. 42.Bagali S, Das KK. Hypoxia and its preconditioning on cardiac and vascular remodeling in experimental animals. Resp Physiol Neurobiol 2021 Mar;285:103588. doi: 10.1016/j.resp.2020.103588 (IF 2.821) (Q2)
  43. 43.Kanthe PS, Patil BS, Das KK. Terminalia arjuna supplementation ameliorates high fat diet-induced oxidative stress in nephrotoxic rats. J Basic Clin Physiol Pharmacol. 2021 Mar 22. doi: 10.1515/jbcpp-2020-0106. PMID: 33743558 (Q3)

Book Chapter

The Perspective of Physiome Modelling in Systems Biology: New Horizon, Systems Biology, Bioinformatics and Livestock Science (2023) 1: 51. Chapter DOI: https://doi.org/10.2174/9789815165616123010008

ISBN
ISBN 978 5165 61 6 (November 2023)
Author
Parvatikar P, Bagali S, Kanthe P, Patil AV, Das KK
Publisher
Bentham Science, UAE

Section 12

Patents and Copyright

Patents

  1. 01Ishwar B Bagoji, Gavishiddappa A Hadimani, R S Bulagouda, Kusal K. Das, S V Patil, Laxman Pathrot. Filed 2020-06-03. Application No. 329782-001 [Granted Patent No. 329782-001 (11/1/2023)]
  2. 02Pharmaceutical formulations of responsive smart hydrogel for transdermal drug delivery. Kulkarni RV, Patil SB, Akamanchi KG, Das KK. Filed 2020-09-20. Published 2020-10-09. Granted Patent No. 439425 dated 19/07/2023

Copyright — Indian Copyright Registration by the Indian Copyright Office

  1. 01Interaction of bioactive molecule of Mucuna pruriens with proteins of Wnt/beta catenin pathway to identify potential candidates for pulmonary hypertension by In silico analysis. Authors: Supriya Bhosale, Prachi Parvatikar, Shrilaxmi Bagali, Kusal K Das
  2. 02Cell signalling in chronic sustained hypoxia: Cardiovascular remodelling, glucose homeostasis and role of dual L/N type calcium channel blocker. Authors: Shrilaxmi Bagali, Kusal K Das
  3. 03Effect of cilnidipine as an antihypertensive agent on two forms (L-NAME & L-NAME+4% NaCl) of hypertensive rats. Authors: Kusal K Das, Gouher Banu Shaikh

Section 13

Collaborations

Prof. L. Lee Hamm, Sr. Vice President & Dean of Tulane University School of Medicine, New Orleans, USA and Prof. M. S. Biradar, Vice Chancellor of BLDE University, Vijayapura, India exchanges greetings after signing MoU between the universities on February 9, 2017 at New Orleans, USA.

India – CCRH

MoU for collaborative research with Central Council for Research in Homeopathy (CCRH) for project entitled “Homeopathic formulation of Crotalus horridus venom for the therapeutic reduction of vascular permeability in haemorrhagic stroke as found in dengue fever”. File No.: 17-47/2023-24/CCRH/Tech/Coll/BLDE University/4926 dated 11.03.24.

USA

Department of Physiology, Tulane University School of Medicine, New Orleans, USA with Prof. L. Gabriel Navar & Prof. D. S. A. Majid (2016–2019). Project I: “Hypoxia, metal exposure and cell signaling pathways: Evaluation of cardiovascular remodelling and renal hemodynamics in male albino rats treated with ascorbate and calcium channel blocker”. An MoU between the two universities had already been done. Project II: “Relationship of urinary AGT to Central Hemodynamics and the Response to Antihypertensive Therapy” jointly with Department of Medicine.

UK

Division of Cardiovascular Medicine & Diabetic Research, School of Medicine, University of Leeds, Leeds, UK with Dr. Sikha Saha on “Hypoxia Preconditioning & Stroke in experimental animals”. Visiting Professors assignments.

Bolivia

High Altitude Pulmonary and Pathology Institute & Zubieta University, La Paz, Bolivia for 3 years (2017–2020) with Prof. Gustavo Zubieta-Calleja on “Hypoxia and High Altitude Cerebral Edema (HACE)”.

Section 14

Doctoral Mentorship

Satish G. Patil2014
Gavish A Hadimani2015
Bheemsetty S. Patil2016
Pallavi Kanthe2016
Ishwar B. Bagoji2016
Shaikh Hussain Saheb2017
Jyoti Khodnapur2018
Rohini Kori2019
Lata Mullur2019
Shrilaxmi Bagali2019
Harish Bhat2019
Anita P. Jawalgi2020
R Chandramouli Reddy2020
Jaysimha Reddy2021
Anita Herur2022
Gouhar Banu Shaikh2023
Rajat V Hegde2023
Ms Sana Kousar Patel2024
Dr Saeed Yendigeri2025
Ms Supriya Bhosale2025
Surekha Hippargi2025

Prof. Kusal Das of LVPM is conducting online PhD Viva of AIIMS-New Delhi candidate.

Section 15

Milestones and Memories from the LVPM Journey

National & International Conferences (2016 onwards)

  1. 01Annual Conference of Association of Physiologists of India (Sep 14-17, 2016) at BLDE University, Vijayapura, Karnataka.
  2. 02Co-organized 7th Chronic Hypoxia Symposium as coordinator during February – March 2019. 7th Chronic Hypoxia Symposium in La Paz, Bolivia (February 28 – March 2019). Prof. M. S. Biradar, Vice Chancellor, BLDE (Deemed to be University) and Advisor of LVPM inaugurated the conference. Prof. Kusal Das was one of the coordinators of this event.
  3. 03Laboratory of Vascular Physiology and Medicine, Department of Physiology organized International Hypoxia Symposium-2019 to commemorate 2019 Nobel Prize awards for hypoxia biologists. Prof. Jan Marino Ramirez, Professor of Neurosurgery, University of Washington, USA, Prof. Gustavo Zubieta-Calleja, Director, IPPA, La Paz, Bolivia, Prof. Thuppil Venkatesh, Emeritus Professor of Biochemistry, St. John’s Medical College, Bangalore and Dr. Bhaskar Saha, Scientist G, NCCS, DBT, Pune delivered lectures. Prof. Jan Marino (Nino) Ramirez received citation from Dr. Bhaskar Saha at the Symposium.

Visiting Professor Positions

  1. 01Prof. Kusal K Das was appointed as Visiting Professor of Medicine at Leeds Medical School, University of Leeds (March 1, 2014 – February 28, 2016).
  2. 02Prof. Kusal Das was appointed as Visiting Professor of Physiology at School of Medicine, Tulane University, New Orleans, 2017.
  3. 03Prof. Dr. M. S. Biradar was appointed as Visiting Professor, Tulane University School of Medicine, USA (2017).

International Visits

  1. 01Prof. Kusal Das – Visiting Professor of Medicine at Leeds Medical School, University of Leeds, UK (2015 June-July).
  2. 02Prof. Kusal Das – Visiting Professor of Medicine at Leeds Medical School, University of Leeds, UK (2016 March).
  3. 03Professor M. S. Biradar, Vice Chancellor, BLDE University and Professor Kusal K. Das, Department of Physiology, BLDE University visited Hypertension & Renal Centre of Excellence at Tulane University School of Medicine, New Orleans, USA from February 2, 2017 to February 17, 2017. Both the Professors of BLDE University, Vijayapura, India delivered invited lectures at Tulane University, USA. Prof. M. S. Biradar & Prof. Kusal Das were honored by Tulane University, USA as Visiting Professors of the University. (2017 February-March)
  4. 04Mr. R. Chandramouli Reddy, JRF visited Vascular Medicine at NUS, Singapore to get training under Dr. Veerendra Chadachan, MD; FRCP who is an Associate Professor at Medical School under NUS, Singapore (December 2017).
  5. 05Prof. Kusal K. Das – National University of Singapore, Singapore as COPE Member, UK (March 2018).
  6. 06Prof. M. S. Biradar and Prof. Kusal K Das visited Yerevan, Armenia to sign Agreement with UNESCO-Chair Life Science to join UNESCO/UNITWIN Network, August 2018.
  7. 07Prof. M. S. Biradar and Prof. Kusal K Das visited La Paz, Bolivia and co-organized 7th Chronic Hypoxia Symposium with Zubieta University, La Paz, Bolivia (February 2019).
  8. 08Prof. M. S. Biradar and Prof. Kusal K Das visited Texas Tech University, El Paso, USA to deliver Lecture and visit the University for Cancer research proposals (March 2020). Renowned endocrinologist and Vice President of the University Prof. Peter Rotwin had a meeting with Vascular laboratory faculty member and Advisor.

External Research Student / Faculty Training

Naira Eloyan (UNESCO PhD Student, Yerevan, Armenia)

Dr. Naira Eloyan, UNESCO PhD student under UNESCO Chair Life Sciences from Yerevan, Armenia had undergone 3-week training at Vascular Laboratory. She was mentored by Prof. Kusal Das, UNESCO Adviser for Environmental Health and PhD Co-Adviser of Dr. Naira Eloyan. Dr. Vidya A. Patil, Professor & Head, Department of Anaesthesia acted as a clinical mentor for Dr. Naira for clinical research training (September – October, 2020).

Dr. Naira was trained in experimental physiology in the perspective of biophysics and molecular biology. She also received clinical training in the Department of Anaesthesia for the management of pain sensation and electromagnetic field.

Natalia Zubieta-DeUrioste (La Paz, Bolivia)

Dr. Natalia Zubieta-DeUrioste, MD – A physician at La Paz, Bolivia at High Altitude Pulmonary and Pathology Institute visited Laboratory of Vascular Physiology and Medicine, BLDE (Deemed to be University) as a research trainee for 2 weeks during November – December 2020. She had a training basically on experimental physiology and molecular biology specific to hypoxia gene here.

Natalia Zubieta-DeUrioste, MD (La Paz, Bolivia)
Natalia Zubieta-DeUrioste, MD (La Paz, Bolivia)
Natalia Zubieta-DeUrioste, MD (La Paz, Bolivia)
Natalia Zubieta-DeUrioste, MD (La Paz, Bolivia)

Satish Dipankar (AIIMS, Patna)

Dr. Satish Dipankar, MD (Physiology), Associate Professor of Physiology, AIIMS, Patna was deputed to Laboratory of Vascular Physiology and Medicine for research training in experimental physiology under Prof. Kusal Das. He was here for 2 weeks during June 2020. During his training he learnt rodent stroke model and experimental hypertension.

Dr. Satish Dipankar, AIIMS, Patna at LVPM
Dr. Satish Dipankar, AIIMS, Patna at LVPM
Dr. Satish Dipankar, AIIMS, Patna is in LVPM as research trainee
Dr. Satish Dipankar, AIIMS, Patna is in LVPM as research trainee

International Visitors

2016 (February)

Dr. Sikha Saha, PhD – Associate Professor of Medicine, University of Leeds, UK and a renowned neuroscientist visited Vascular laboratory as a Visiting Fellow of BLDE (Deemed to be University) during February 2016 for 2 weeks. She trained the scholars and faculty members on the techniques of rodent stroke model. Dr. Sikha Saha is Associate Professor and Director-Innovation at University of Leeds, UK.

2017 (December)

Dr. Gustavo Zubieta-Calleja, MD, Director of High Altitude Pulmonary and Pathology, La Paz, Bolivia and Prof. Dewan S. A. Majid, MD; PhD, Professor of Physiology, Tulane University, New Orleans, USA visited BLDE (Deemed to be University), Vijayapur during December 2017. They have worked at Laboratory of Vascular Physiology and Medicine and demonstrated many experiments to the scholars of the laboratory.

2019 (August)

Robert G. Carroll, PhD – Professor of Physiology and Associate Dean of Medical Education, BRODY School of Medicine, East Carolina University, NC, USA has visited BLDE (Deemed to be University) as a Visiting Professor of Medical Education. Prof. Carroll is also the Chair of IUPS (Education Committee) for which Prof. Kusal Das is a member. Professor Carroll interacted with research scholars of the vascular laboratory and suggested many things to promote physiology research.

2019 (November – December)

Prof. Jan-Marino Ramirez, Professor and Director of Department of Neurosurgery, University of Washington, USA and Prof. Gustavo Zubieta-Calleja, Professor and Director of High Altitude Pulmonary and Pathology Institute visited Laboratory of Vascular Physiology and Medicine, Shri B. M. Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University) during November – December 2019. Prof. Ramirez was accompanied by his spouse Dr. Erika Ramirez and Prof. Gustavo was with his family.

National Dignitaries

  • Prof. Ashok K. Mishra, FNASc, Dean (Academics & Research), IIT-Madras (August 2019) at Vascular laboratory.
  • Dr. Shashi Bala Singh, D.Sc; FNASc; FAMS, Director-NIPER-HYD and Former Director General (LS)-DRDO during September 2019.
  • Prof. C. K. Kokate, Former Vice Chancellor Kakatiya University & KLE University and renowned pharmaceutical scientist visited LVPM during December 2019.
  • Dr. Bhaskar Saha, FNA; FNASc; FASc and recipient of S. S. Bhatnagar Award visited LVPM for research collaboration during January 2020.

Section 16

Contact

Dr Shrilaxmi Bagali, MD; PhD

Professor (Addl.)

Assistant Director and Co-ordinator

Laboratory of Vascular Physiology and Medicine

Department of Physiology

Tel: 91-8352 262770 (Extension 2262)

research@bldeuniversity.ac.in

Dr Lata Mullur, MD; PhD

Professor and Head, Department of Physiology

Shri B. M. Patil Medical College, Hospital & Research Centre

BLDE (Deemed to be University), Vijayapura, Karnataka

Tel: 91-8352 262770 (Extension 2262)

lata.mullur@bldedu.ac.in