Distinguished Chair Professor
Laboratory of Vascular Physiology & Medicine,
Department of Physiology, Shri B.M.Patil Medical College,
Hospital & Research Centre
Director – Center for Advanced Medical Research
BLDE (Deemed to be University),
Vijayapura-586103, Karnataka, India
Tel: 91 8352 262770 (Ext.2262);
Mobile: 9448194257,
Email: kusaldas@yahoo.com & kusaldas@bldedu.ac.in
Website: https://www.bldedu.ac.in/kusal-k-das/
IRINS: https://bldedu.irins.org/profile/44862

Honorary Fellow, Karnataka Science & Technology Academy Department of Science & Technology, Government of Karnataka
INTERNATIONAL POSITION:

2020 –  Dean, Department of Environmental Health, UNESCO Chair Life Sciences  (Biophysics, Biotechnology & Environmental Health). Weblink: http://www.biophys.am/pages/index/Environmental-Health/ ]

FIELD OF SPECIALIZATION AND EXPERTISE:

Physiological Sciences. Expertise in mammalian oxygen-sensing mechanisms including oxygen sensing gene expression during chronic and intermittent hypoxia with or without heavy metals (nickel, lead, and chromium VI)

BRIEF CRITICAL VIEWS ON MY CONTRIBUTION TOWARDS THE ADVANCEMENT OF SCIENCES:

I did Ph.D. in Physiology from the University of Calcutta and his thesis (1993)was entitled “Metallic Pollution: It’s effect on male reproductive system with special references to protein inadequacy”. My earlier research works basically on heavy metal toxicities and how these metals especially divalent cation alters system biology. My research established a link between nutritional role especially dietary protein and severity of impaired functional biology including reproductive health in experimental animals. I exclusively worked on changes in DNA, RNA, and genetic information systems due to heavy metal assaults in albino rats in relation to dietary proteins and antioxidant vitamins particularly Vitamin C and E (Das &Dasgupta 1997; Das &Dasgupta 2000; Das &Dasgupta 2002; Das et al 2020). My team’s works on vitamin C and E against nickel, Cr VI and Pb treated pathophysiology of the cardiovascular, renal, pulmonary, reproductive, and hepato-billiary system are noteworthy (Gupta 2008; Das 2015). Our works also showed an elevation of serum glucose level in rats supplemented with a megadose of vitamin C as l-ascorbic acid. Further of his research extended to human occupational exposure to heavy metals especially on lead (Pb) and oxidative stress though NF-kβ (Das et al 2011; Chadchan et al 2014; Mantur et al 2014; Das et al 2016; Das et al 2017).
Further, our research on experimental biology progress on low oxygen microenvironment in rodents especially in chronic sustained and intermittent hypoxia in experimental animals treated with heavy metals (Nickel and Lead). These work outcomes showed cell signal transduction in hypoxia exposed animals in system biology though hypoxia sensitive genes like hypoxia-inducible factor-1α (HIF-1α), erythropoietin (EPO), and vascular endothelial growth factor (VEGF) expressions in presence of divalent cation metals (Hattiwale et al 2013; Das et al 2015; Reddy et al 2020). Further, we had done extensive research on the regulation of vascular endothelial and smooth muscle integrity though NOS3/NOS2 gene expression in hypoxia exposed rodents (Patil et al 2015; Das and Saha 2014). One of our works on hypoxia, divalent heavy metals, and glucose intolerance in rodents showed the definite involvement of L/N type of calcium channel and cardiac autonomic dysfunctions with both chronic sustained and intermittent hypoxia. This work suggests possible therapeutic uses of L/N type of calcium channel blockers to control hypoxia or metal-induced hyperglycemia. We have also engaged in research on aging-related oxygen sensing gene and vascular physiology relationship especially on arterial stiffness including augmented index in humans (Das et al 2016, Das et al 2017; Khodnapur& Das 2021).
Our group invented a new modified method of estimation of serum Vitamin E (α-tocopherol) which is economic, less tedious, and less time consuming (Jargar et al 2012). This invention made us get The Physiological Society, UK scholarship to the University of Edinburgh.
Currently, we are working on isolation of specific bioactive compounds from plants origin of north Karnataka and elsewhere to develop drug(s) against ‘stroke’ and cardiovascular pathophysiology ( Kanthe et al 2021). Our Laboratory of Vascular Physiology and Medicine laboratory established the complex technique of rodent stroke model by middle cerebral artery occlusion (MCAO) technique. Our works on hypoxia preconditioning in cerebral ischemia as a preventive measure made us internationally known by scientific and peer researchers (Bagali& Das,2021; Das et al 2021 )Our laboratory is also working on computer-aided drug discovery through computational biology and Artificial Intelligent (Parvatikar, et al 2021)
I and my team also contributed a lot to environmental biology especially on groundwater arsenic and fluoride contamination in north Karnataka, India. He is one of the first to describe overt arsenicosis in such an area as well as in this region of Karnataka, India (Chakrabarti et al 2013). For this work I had been conferred “Dr.Raja Ramanna State Scientist Award 2015” by the Government of Karnataka, India.https://www.kscst.org.in/awards_2013_2014/st_awards_2013_2014.html ). My contribution in hypoxia pathophysiology research is recognized with “Science, Honor & Truth Medal 2016” conferred by High Altitude Pulmonary and Pathology Institute, Zubieta University, Bolivia (https://www.altitudeclinic.com/award.html).
Further, I had been conferred “G.P.Chatterjee Memorial Research Award 2019” by ISCA, Ministry of Science & Technology, Government of India (http://sciencecongress.nic.in/isca_awardees_2018-19.php) for research on fluoride toxicities in Indi taluk of Vijayapur district, Karnataka, India (Ugran et al 2016).

REFERENCES:
  1. Das, KK, Dasgupta S: Alteration of testicular biochemistry during protein restriction in nickel treated rats..Biol Trace Element Res1997; 60(3):243-9.
  2. Das KK, Dasgupta S. Effect of nickel on testicular nucleic acid concentrations of rats on protein restriction..Biol Trace Elem Res 2000; 73(2):175-80.
  3. Das KK, DasguptaS.Effect of nickel sulfate on testicular steroidogenesis in rats during protein restriction.. Environ Health Perspect 2002; 110(9):923-6
  4. Das S, Reddy RC, Chadchan KS, Patil AJ, Biradar MS, Das KK. Nickel and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C. EndocrMetab Immune Disord Drug Targets. 2020;20(7):1024-1031. doi: 10.2174/1871530319666191205122249
  5. Gupta AD, Das SN, Dhundasi SA, Das KK. Effect of garlic (Allium sativum) on heavy metal (nickel II and chromium VI) induced alteration of serum lipid profile in male albino rats..Int J Environ Res Public Health 2008; 5(3):147-51
  6. Das KK,Jargar JG, Saha S, Yendigeri SM, Singh SB. α – Tocopherol supplementation prevents lead acetate and hypoxia induced hepatic dysfunction. Indian J Pharmacol 2015; 47(3):285-291
  7. Das KK, Dhundasi SA, Das SN. Hexavalent chromium and its effect on health: possible protective role of garlic (Allium sativum Linn).. J Basic Clin Physiol Pharmacol 2011; 22(1-2):3-10.
  8. Chadchan K, Das SN; Das KK. Fenugreek (Trigonellafoenumgraecum) leaves extract and its interaction with heavy metal (Nickel II) with reference to glucose reduction capabilities in-vitro. Biomedicine 2014; 34(1):104-108.
  9. Mantur VS, Sommanavar MS, Yendegiri SM, Das KK,Goudar SS. Ameliorating effect of black tea extracts on cadmium chloride –induced alteration of serum lipid profile and liver histopathology in rats. Indian J Physiol Pharmacol 2014;58(2): 128-132
  10. Das KK, Razzaghi-Asl N.; Tikare SN, Di Santo R, Costi R; Messore A; Pescatori L; Crucitti GC; Jargar JG; Dhundasi SA; Saso L. Hypoglycemic activity of curcumin synthetic analogs inalloxan-induced diabetic rats. J Enzyme Inhib Med Chem 2016;31(1):99-105
  11. Das KK, Chadchan KS, Reddy RC, Biradar MS, Kanthe P, Patil BS, AmbekarJG,Bagoji IB, Das S. Effects of some indigenous plants of north Karnataka (India) on cardiovascular and glucose regulatory systems in diabetic rats. Cardiovasc Hematol Agents Med Chem 2017; 15(1): 49-61. DOI:
  12. Reddy RC, Devaranavadagi B, Yendigeri SM, Bagali S, Kulkarni RV, Das KK. Effect of L-Ascorbic Acid on Nickel-Induced Alteration of Cardiovascular Pathophysiology in Wistar Rats. Biol Trace Elem Res.2020 ; 195(1):178-186. DOI: 10.1007/s12011-019-01829-w.
  13. Hattiwale SH, Saha S, Yendigeri SM, Jargar JG, Dhundasi SA, Das KK. Protective effect of L-ascorbic acid on nickel-induced pulmonary nitrosative stress in male albino rats. Biometals 2013; 26(2), 329-336
  14. Das KK, Saha S. Hypoxia, Lead Toxicities and Oxidative stress: Molecular interactions and antioxidant (Vitamin C) defense Current Signaling Transduction & Therapy 2014;9:113-122
  15. Patil SG, Aithala M, Das KK. Evaluation of arterial stiffness in elderly with prehypertension. Indian J Physiol Pharmacol 2015; 59(1): 16-2
  16. Das KK, Nemegouda SR, Patil SG, Saha S. Possible Hypoxia Signaling Induced Alteration of Glucose Homeostasis in Rats Exposed to Chronic Intermittent Hypoxia – Role of Antioxidant (Vitamin C) and Ca2+ Channel Blocker (Cilnidipine)Current Signal Transduction Therapy 2016,11(1): 49-55.
  17. Das KK, Das S, Ambekar JG. Hypoxia and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C and Cilnidipine. In Angel Catala (ed). “Lipid Peroxidation: Inhibition, Effects and Mechanisms”.Chapter 11, 2017; ISBN 978-1-53610-506-3; Nova Science Publishers, NY
  18. Khodnapur JP, Das KK. Age-associated changes in vascular health and its relation with erythropoietin. Indian J Physiol Pharmacol 2021;65(2):119-26.
  19. Jargar JG, Hattiwale SH, Das S, Dhundasi SA, Das KK. A modified simple method for determination of serum α-tocopherol (vitamin E). J Basic Clin Physiol Pharmacol 2012; 23(1):45-8.
  20. Kanthe, P.S., Patil, B.S., Das, K.K, Parvatikar PP. Structural analysis and prediction of potent bioactive molecule for eNOS protein through molecular docking. In Silico Pharmacol.9: 48 (2021). https://doi.org/10.1007/s40203-021-00106-w
  21. Bagali S, Das KK. Hypoxia and its preconditioning on cardiac and vascular remodelling in experimental animals.. 2021 Mar;285:103588. doi: 10.1016/j.resp.2020.103588
  22. Das S, Reddy RC, Chadchan KS, Patil AJ, Biradar MS, Das KK. Nickel and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C. Endocr Metab Immune Disord Drug Targets. 2020;20(7):1024-1031. DOI: 10.2174/1871530319666191205122249.:
  23. Parvatikar PP, Patil S, Hosker J, Swargam S, Kulkarni RV,Das KK. Screening and Development of Transglutaminase-2 Inhibitors and their Derivative as Anti-lung Cancer Agent by in silico and in vitro Approaches”, Current Computer-Aided Drug Design 2021; 17. https://doi.org/10.2174/1573409917666210322120350
  24. Chakraborti D, Rahman MM, Murrill M, Das R, Siddayya, Patil SG, Sarkar A, Dadapeer H J, Yendigeri SM, Ahmed R, Das KK.Environmental arsenic contamination and its health effects in a historic gold mining area of the Mangalur greenstone belt of Northeastern Karnataka, India.. J Hazard Mater 2013; 15; 262:1048-55
  25. UgranV,Desai N, ChakrabortiD,MasaliKA,Mantur P, Kulkarni S,DeshmukhN,ChadchanKS,DasSN,Tanksali AS, ArwikarSP,Guggarigoudar SP, VallabhaT,Patil SS, Das KK. Groundwater fluoride contamination and its possible health implications in Indi taluk of Vijayapura District (Karnataka State), India..Environ Geochem Health.2017 Oct;39(5):1017-1029. DOI: 10.1007/s10653-016-9869-2
INVENTION OF NEW METHOD TO DETERMINE BLOOD VITAMIN E (Α-TOCOPHEROL)

Invented a novel procedure for the specific and quantitative determination of α -tocopherol (vitamin E) in serum. Our modified method affords several advantages (i.e., simple, suitable, less tedious, economic, rapid, and utilizes a small quantity of serum) over existing methods (Das et al 2013).
The current modified method is based on the previous baker and Frank method and the method of Martinek by using 2,2 ′ -bipyridyl, ferric chloride, and xylene. The complex of ferrous ions generated in this reaction with 2,2 ′ -bipyridylis was determined by using a plain enzyme-linked immunosorbent assay microplate (non-antibody coated) at 492 nm (Jargar et al 2012). This invention has brought to me “Shri Dev Raj Bajaj Memorial Research Prize 2014” conferred by the Association of Physiologists and Pharmacologists of India, Regd. office at AIIMS, New Delhi.

THE TECHNICAL SKILLS TO HANDLE BIOLOGICAL INSTRUMENTS:
  1. Expertise in handling different models of rats and mice as following:-
    • Chronic sustained hypoxia model (10% Oxygen; 90% N2)
    • Chronic intermittent hypoxia model (10% Oxygen; 90% N2)
    • Rodent stroke model by mid cerebral carotid artery occlusion(MCAO) technique
    • Protein restricted dietary model (5% Casein)
    • Hyperlipidemia dietary model in rats (30% fat)
    • Salt sensitive hypertensive (SSH) models by inducing L-NAME &NaCl
    • Renal arterial occlusion model for developing renal hypertension
  2. Well versed in handling Atomic Absorption Spectrophotometry to evaluate serum nickel and Cr VI concentrations as part of his research on metal toxicities in biological systems and environmental health research like groundwater arsenic concentration estimations.
  3. Experienced with working on electrophysiology setup in both humans and rodents. He is trained in handling ECG, EMG, EEG, and all the cardiovascular electrophysiological assessments including heart rate variability (HRV), small animal radiotelemetry devices, baroreceptor sensitivity tests (BRS) by using epinephrine and sodium nitroprusside techniques. These understandings are necessary for work on the hypoxia model in rats and mice.
  4. Experienced with the techniques of invasive blood pressure measurement through femoral/iliac artery of rats.
  5. Experience in central blood pressure measurements and arterial stiffness including augmented index and pulse wave velocity measurements through periscope and plethysmograph.
  6. Trained in ELISA, Western blotting, and PCR for quantitative and qualitative assessment for various Well-versed with various chromatographic techniques including HPLC.
THE PROFESSIONAL CAREER AS A PHYSIOLOGY TEACHER:

I am working in the area of biological sciences since his doctoral curriculum. I pursued a Master’s and Ph.D. in Human Physiology at the University of Calcutta. I also did his Bachelor of Science degree with Honours in Physiology from Presidency College, Kolkata.

I have a long-standing academic and research career in biological sciences. I am teaching Physiology in the medical school of India since 1989 for MBBS, BDS, MD, M.Sc students. I was also Visiting Professor of Physiology under the Faculty of Medicine in the School of Medicine, University of Leeds, UK (2014-2016) and Visiting Professor of Physiology at Tulane University School of Medicine, USA ( 2017).

I have successfully supervised/co-supervised22 Ph.D. and 10 MD (Physiology) students under Rajiv Gandhi University of Health Sciences, Karnataka, BLDE (Deemed to be University), Vijayapur, Vidyasagar University, West Bengal, KLE University, Belagavi, and KIMS Deem University, Karad, India. I was a member of the PG Board of Studies and Ph.D. Registration committee of  Rajiv Gandhi University of Health Sciences, Bangalore.

At present, I am a Member of the Education Committee of the International Union of Physiological Sciences (IUPS). I am also the Vice President of The Physiological Society of India (2020-2023) and President of the South Asian Association of Physiologists (SAAP) at the University of Colombo, Sri Lanka.

  • Teaching;

Teaches MBBS, BDS, MBChB (UK), MD, PhD students

  • Distinguished Chair Professor, , Faculty of Medicine, BLDE University, Bijapur, Karnataka since August 25, 2020
  • Professor of Physiology, Faculty of Medicine, BLDE University, Vijayapur, Karnataka since 21st June 2013- till August 24, 2020
  • Visiting Professor (2017), Tulane University School of Medicine, New Orleans, USA
  • Visiting Professor (2014-2016), Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, UK
  • Professor of Physiology [2006 – 21st June 2013]- Al Ameen Medical College, Bijapur, Karnataka, India
  • Honorary Professor of Physiology, Al Ameen Dental College, Bijapur, Karnataka [1992- 06.2013]
  • Additional Professor of Physiology[2001-2006]- Al Ameen Medical College,Bijapur
  • Associate Professor of Physiology [1996-2001]- Al Ameen Medical College, Bijapur,

Karnataka

  • Assistant Professor of Physiology [1990-1996]- Al Ameen Medical College, Bijapur, Karnataka
  • UGC Junior Research Fellow [1986 – 1989] –Department of Physiology, University of Calcutta.
THE VALUE OF MY WORKS IN THE PROGRESSION OF THE SCIENCES:

My research in basic biological sciences is extended to clinical medicine in general My works on heavy metals (nickel, chromium VI, lead, and cadmium) induced alteration of system biology are cited in WHO, EPA (ATSDR), etc. Our invention of a new and modified method of serum vitamin E estimation is widely cited and used in many diagnostic laboratories.  My team’s works on hypoxia biology also help to progress understanding of various respiratory diseases and uses of certain drugs like cilnidipine (calcium channel blocker) to treat chronic obstructive pulmonary disease. Further our works on plant extract to treat diabetes and the recent isolation of bioactive compounds from certain indigenous plant extracts to treat against cerebral ischemia or ischemic stroke is definitely fascinating and plays a pivotal role in the progression of medical sciences.

UNESCO/ UNITWIN Network under UNESCO Chair- Life Sciences:

Laboratory of Vascular Physiology and Medicine becomes the Coordinating centre for training PhD students in Environmental Health research. This Interregional network on PhD Education and Research in Biophysics, Biotechnology and Environmental Health is under UNESCO Chair Life Sciences. Prof.KusalK.Das is appointed as Coordinator for Environmental Health (2019-2024).

Link:http://www.biophys.am/pages/index/About-the-Network

Currently, I am the Dean of Environmental Health under UNESCO Chair Life Sciences

(http://www.biophys.am/pages/index/Environmental-Health/)

PATENT:
  1. Novel Embalming Machine. Gavishiddappa A Hadimani, Ishwar B Bagoji, R S Bulagouda, Kusal Das, AravindPatil, LaxmanPathrot. Filing Date- 2020-06-03.Published 2020-07-30. Application No. 202041023339. Embalming Machine.
  2. Ishwar B Bagoji, Gavishiddappa A Hadimani, R S Bulagouda, Kusal Das, S V Patil, LaxmanPathrot. Filed 2020-06-03. Application No. 329782-001
  3. Pharmaceutical formulations of responsive smart hydrogel for transdermal drug delivery. Kulkarni RV, Patil SB, Akamanchi KG, Das KK. Filed 2020-09-20. Published 2020-10-09. Application No. 202041040723 A
  4. Pharmacological composition of electrically-sensitive polyacrylamide -grafted-gum tragacanth copolymer for electro-modulated transdermal drug delivery. Kulkarni RV, BirajdarBP,Akamanchi KG, Biradar MS, Das KK. Filed 2020-09-30. Published 2020-10-09. Application No. 202041042648 A
MENTORSHIP:
  • Postdoctoral: 02 (01 completed)
  • Ph.D.(Medical) /Ph.D. (Science)–Awarded22
  • Ph.D. (Medical) –Submitted 01
  • Ph.D. (Medical & Allied Health Sciences)- Current 06
  • MD(Physiology)- Awarded 10
  • My Ph.D./MD research scholar Dr.SatishG.Patil (2011-2014), Dr.IshwarBagoji (2013-1016), Dr.G.A.Hadimani ( 2013-2015), Dr.ShrilaxmiBagali (2015-2018), Dr.SaeedYendegir (2014-2018), and Dr.LataMullur (2014-2018) have been awarded “Research Gold Medals” by BLDE University and in 2014 Dr.SatishG.Patil received DST-Inspire Fellowship (2011-2014) and was also awarded the “Young Researcher Award 2013” at 9TH European Congress of Geriatric Medicine in Venice, Italy. Dr.Amrita Das Gupta was awarded ‘Vidyasagar University Young Scientist Award 2005’ and “Prof.B.B.Sarkar Memorial Research Prize of PSI – 2006”. Dr.SwatiTikare was awarded the ‘Prof.B.B.Sarkar memorial Research Prize 2008” by PSI. Dr.Jameel G. Jargar was awarded the “KSCST Science Talent Award 2015 by the Government of Karnataka”.
PEER ASSESSOR:

(1) National Institutional Ranking Framework (NIRF) 2018, 2019, 2020& 2021, MHRD, Government of India.

(2) QS Global Academic Survey- March 2018, 2019& 2020.SERB-DST, Government of India for National Postdoctoral Fellowship (N-PDF), 2018& 2019

(3) Member of Faculty recruitment –

– Department of Physiology, University of Kalyani, West Bengal in 2006 & 2008

– Recruitment and Assessment Committee, DRDO (LS) in 2010

– NEIGRIMS, Shillong for selection of Professor position, Govt.of India in 2018.

NUMBER OF RESEARCH/TECHNICAL PAPERS, BOOKS PUBLISHED (AS OF JULY 2021):

Publications list

Books

NoTitleISBNAuthorPublisher
1.

Free Radicals Medicine and Biology.

May-June 2020

ISBN 978-1-78985-144-1Kusal K Das. Swastika Das, MallanagoudS.BiradarInTech, London SE1 9SG
2.Hypoxia and Anoxia, Oct 26,2018978-953-52-6485-2

Kusal K.Das&

M.S.Biradar

InTech, London SE1 9SG
3.Antioxidant (L-Ascorbic Acid and L- tocopherol) on Nickel Toxicities: Role of Vitamin C and E on Nickel Toxicities. May 2010

ISBN-13: 978-3838357713

Kusal K.DasLAP Publishing, Koln, Germany
4.

Garlic on Nickel & Chromium VI toxicities in diabetic rats.

August 2010

ISBN-13: 978-3639259254Kusal K.DasVDM-Verleg, Suurbuchen, Germany

Book Chapters

No.TitleISBNAuthor

Publisher

 

1.

Introductory Chapter: Free Radical Biology in Metal Toxicities—Role of Antioxidants. In book; Free Radicals Biology and Medicine, Chapter 1

DOI: DOI: 10.5772/intechopen.92164

(Das KK edited)

ISBN: 978-1-78985-144-1

(July 2020)

Das S,Bagali S, Das SK et alInTech open, London
2.

Polysaccharide-based stimuli- 7 sensitive graft copolymers for drug delivery. In book: Polysaccharide Carriers for Drug Delivery

Edition: 1st; Chapter: 7.

DOI: 10.1016/B978-0-08-102553-6.00007-6

(Maiti S, Jana S eds)

ISBN: 978-0-08-102553-6

(June 4, 2019)

Kulkarni RV, Inamadar SZ, Das KK, Biradar MS

Elsevier Inc, USA

3Heavy metals and low oxygen microenvironment: Its impact on liver metabolism and dietary supplementation. In RR Watson & V. Preedy(ed) “Dietary intervention in liver diseases”, Chapter  28;  2019

ISBN 9780128144664; Elsevier, (February1,2019)

 

Das KK, Honutagi R, Mullur L et al

Elsevier Inc, USA

Academic Press, NY

4Introductory Chapter-Primary concept of hypoxia and anoxia In ; Hypoxia and anoxia (Das KK, Biradar MS eds), 2018

ISBN: 978-953-51-6485-2

(Dec 24 2018)

Bagali S, Hadimani GA, Biradar MS, Das KKInTech  Open Science, London
5Hypoxia and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C and Cilnidipine. In Angel Catala (ed). “Lipid Peroxidation: Inhibition, Effects and Mechanisms”.Chapter 11, 2017

 

ISBN 978-1-53610-506-3

(Jan 18, 2017)

Kusal K Das, Swastika Das, Jeevan G.AmbekarNOVA Science Publishers,NY,USA
6

 

Ethical Publications in Medical Research. In Peter A.Clark (ed) “Bioethics – Medical, Ethical and LegalPerspectives”, Chapter 13,2016

 

 

ISBN 978-953-51-4934-7.

(Dec.24. 2016)

 

Kusal K.Das, Malannagoud S. Biradar

 

InTech  Open Science, Rijeka, Croatia, EU

7Can yoga protect vascular integrity in ageing ? In: P.S.Shankar, M.S.Biradar (ed). Current Issue in Geriatrics, Vol.4;2016,

 

ISBN 97893-5258-9791

(2016)

 

Satish G.Patil, KusalK.Das

 

Geriatric Society of India, New Delhi

8

Nickel: Molecular Diversity, Application,

Essentiality and Toxicity in human health. In Gaillard Blanc and Damien Moreau

(Eds) in Biometals,: Molecular Structures, Binding Properties and Applications,2010 ,

pp 33-58

ISBN 978-1-60876-852-3

(Oct 5 2010)

Kusal K Das , Swastika N.Das,  Salim A.DhundasiNova Science Publishers Inc; New York, USA
9

Nickel Toxicities: Role of Oxidative Stress

and Protective Antioxidants(L-Ascorbic Acid and Alpha-tocopherol). In Khanna

GL( Eds.), Physiology for Therapeutic and Rehabilitation Practices-Current

Approaches. 2008; pp 51-54

ISBN-13: 978-8173199202
(March 2008)

Kusal K Das, Amrita Das Gupta, Salim A.Dhundasi

Narosa Publishing House Pvt.Ltd; New Delhi, India

 
SCHOLARLY RESEARCH PUBLICATIONS (TOTAL-111; SCOPUS- 106):

(SCOPUS ID: 56274121000/ ORCID ID :0000-0002-3641-2117)

  1. Khodnapur JP, Das KK. Age-associated changes in vascular health and its relation with erythropoietin. Indian J Physiol Pharmacol 2021;65(2):119-26.
  2. Parvatikar PP, Patil S, Hosker J, Swargam S, Kulkarni RV,Das KK. Screening and Development of Transglutaminase-2 Inhibitors and their Derivative as Anti-lung Cancer Agent by in silico and in vitro Approaches”, Current Computer-Aided Drug Design 2021; 17. https://doi.org/10.2174/1573409917666210322120350 ( IF: 1.66 )
  3. Kanthe, P.S., Patil, B.S., Das, K.K, Parvatikar PP. Structural analysis and prediction of the potent bioactive molecule for eNOS protein through molecular docking. In Silico Pharmacol.9: 48 (2021). https://doi.org/10.1007/s40203-021-00106-w
  4. Hegde S, Hegde R, Kulkarni SS, Das KK, Gai PB, Bulgouda R. Molecular alteration in the Gap Junction Beta 2 (GJB2) gene associated with non-syndromic sensorineural hearing impairment. Intractable and Rare Diseases Research 2021;10: 31-36
  5. Bagali S, Das KK. Hypoxia and its preconditioning on cardiac and vascular remodeling in experimental animals.. 2021 Mar;285:103588. DOI: 10.1016/j.resp.2020.103588.{1F; 1.931)
  6. Kanthe PS, Patil BS, Das KK. Terminalia arjunasupplementation ameliorates high fat diet-induced oxidative stress in nephrotoxic rats. J Basic Clin Physiol Pharmacol. 2021 Mar 22. DOI: 10.1515/jbcpp-2020-0106. Epub ahead of print. PMID: 33743558.
  7. BagaliS, Nerune SM, Reddy RC, Yendigeri SM, Patil BS, Naikwadi AA , KulkarniRV, Das KK. Low oxygen microenvironment and cardiovascular remodeling: Role of dual L/N type Ca2+ channel blocker. Indian J Pharmcol 2020, 52(4): 383-391(1.02)
  8. Shaikh GB, Hippargi S, Majid DSA, Biradar MS, Das KK. Effect of L/N-type Calcium Channel Blocker (Cilnidipine) on Oxidative Stress in Nitric Oxide deficient Hypertensive Rats. J Krishna Inst Med Sci Univ2020; 9(2): 73-80.
  9. Zubieta-Calleja, G.R.; Zubieta-DeUrioste, N.; Venkatesh, T.; Das KK.; Soliz, J. COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor ’s-Eye-View. Reviews on Recent Clinical Trials 2020, 15(4). https://doi.org/10.2174/1574887115666200925141108
  10. Das KK. Meet our Editorial Member. Reviews on Recent Clinical Trials 2020;15(2):83. 2174/157488711502200515085551
  11. Patil SB Inamdar SZ, Das KK,.Akamanchi KG, Patil AV, Inamadar AC,  Reddy KR, Kulkarni Tailor-made electrically-responsive poly(acrylamide)-graft-pullulan copolymer-based transdermal drug delivery systems: Synthesis, characterization, in-vitro and ex-vivo evaluation. J Drug Delivery Sci-Tech 2020; DOI: 10.1016/j.jddst.2020.101525 (IF.3.981)
  12. Patil SB, Inamdar SZ, Akamanchi KG, Inamadar AC, Reddy KR, AV, Das KK, Kulkarni Functionally Tailored Electro-sensitive Poly(Acrylamide)-G-Pectin Copolymer Hydrogel for Transdermal Drug Delivery Application: Synthesis, Characterization, In-vitro and Ex-vivo Evaluation. Drug Delivery Letters 2020; DOI10.2174/2210303110666200206114632.
  13. Das S, Reddy RC, Chadchan KS, Patil AJ, Biradar MS, Das KK. Nickel and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C. Endocr Metab Immune Disord Drug Targets. 2020;20(7):1024-1031. DOI: 10.2174/1871530319666191205122249.: (3.05)
  14. Reddy RC, Devaranavadagi B, Yendigeri SM, Bagali S, Kulkarni RV, Das KK. Effect of L-Ascorbic Acid on Nickel-Induced Alteration of Cardiovascular Pathophysiology in Wistar Rats. Biol Trace Elem Res.2020 ; 195(1):178-186. doi: 10.1007/s12011-019-01829-w. (3.738)
  15. Tikare SN.Siddiq M., Das KK.Yendigeri S.Dhundasi SA. Does serum ferritin concentration influence antioxidant Vitamin C in type 2 diabetes? Indian Journal of Public Health Research and Development, 2019, 10(12):300-304
  16. BS, Kanthe P, Reddy RC, Das KK.EmblicaOfficinalis (Amla) ameliorates high fat diet induced alteration of cardiovascular pathophysiology. CardiovascHematol Agents Med Chem.2019;17(1):52-63. doi: 10.2174/1871525717666190409120018.
  17. Boppana R, Raut SY, Mohan GK, Sa B, MutalikS,Reddy KR, Das KK, Biradar MS, Kulkarni RV. Novel pH-sensitive interpenetrated network polyspheres of polyacrylamide-g-locust bean gum and sodium alginate for intestinal targeting of ketoprofen: In vitroand in vivo .Colloids and Surfaces B: Biointerfaces 2019; 180:362-370.https://doi.org/10.1016/j.colsurfb.2019.04.060(IF.5.268)
  18. Bagali S, Naikwadi A, Das KK. Tissue specific effects of chronic sustained hypoxia on oxidative stress: Role of cilnidipine, a dual L/N type Calcium Channel Blocker. J Krishna Inst Med Sci Univ 2019; 8(1);31-36.
  19. Bhat H.,Ambekar JG,,Harwalkar AK,Dongre N, Das KK.Serum VEGF and TNF-α correlate bacterial burden in pulmonary tuberculosis. Indian J Pub Health Res Dev 2019; 10(1):189-194
  20. Das KK, Yendigeri SM, Patil BS, Bagoji IB, Reddy RC, Bagali S, Biradar MS, Saha S. Subchronic hypoxia pretreatment on brain pathophysiology in unilateral common carotid artery occluded albino rats. Indian J Pharmacol 2018;50(4): 185-191. (1.03)
  21. Das KK, Reddy RC, Bagoji IB, Das S, Bagali S, Mullur L, Khodnapur J, Biradar MS. Primary concepts of nickel toxicity; An overview. J Basic ClinPhysiolPharmacol 2018 , 30(2):141-152 https://doi.org/10.1515/jbcpp-2017-0171
  22. Bhat H, Ambekar JG, Harwalkar AK, Dongre N, Das KK. Role of TNF-α on the Function of Erythropoietin and Haematological Profile in Pulmonary Tuberculosis Patients. J ClinDiag Res 2018; DOI: 10.7860/JCDR/2018/36754.0000 ; 12 (8):BC01-04
  23. Khodnapur JP, Aithala MR, Das KK. Serum Vascular Endothelial Growth Factor and Aging: Study among Urban Population of Vijayapur, Karnataka, India. J ClinDiag Res 2018; 12(3):CC05-CC08
  24. Khodnapur JP, Aithala MR, Das KK. Ageing and Pulse Wave Velocity in Relation to Serum Nitric Oxide. J Krishna Inst Med Sci Univ 2018; 7(1);25-38
  25. Kanthe PS, Patil BS, Shrilaxmi C Bagali SC, Reddy RC, Aithala MR, Das KK. Protective effects of Ethanolic Extract of Emblica Officinalis (amla) on Cardiovascular Pathophysiology of Rats, Fed with High Fat Diet. J ClinDiagn Res. 2017, 11(9): CC05-CC09; DOI: 10.7860/JCDR/2017/28474.10628
  26. Kanthe PS, Patil BS, Aithala MR, Das KK. Effect of ethanolic extract of emblica officinalis (Amla) on glucose homeostasis in rats fed with high fat diet. J Krishna Inst Med Sci Univ 2017; 6(3);31-37
  27. Das KK, Chadchan KS, Reddy RC, Biradar MS, Kanthe P, Patil BS, AmbekarJG,Bagoji IB, Das S. Effects of some indigenous plants of north Karnataka (India) on cardiovascular and glucose regulatory systems in diabetic rats. CardiovascHeamatol Agents Med Chem 2017; 15(1): 49-61. DOI: 10.2174/1871525715666170712121347
  28. Chadchan KS, Das SN, Jargar JG, Das KK. A comparative study on Anti-diabetic effects of aqueous Trigonellafoenumgraecum, Hibiscus cannabinus Linn, and Cicer arietinum extracts on Alloxan induced Diabetic Male Albino Rats. J Young Pharm. 2017;9(2):230-3
  29. Kori RS, Aladkatti RH, Desai SD, Das KK. Effect of Anti-stress Activity of Fluoxetine on Restrained Stress Induced Male Albino Rats in He­matological Parameters and Whole Brain Histopathology. J Young Pharm. 2017;9(2):246-50.
  30. Patil SG, Patil SS, AithalaMR,Das KK: Comparison of yoga and walking-exercise on cardiac time intervals as a measure of cardiac function in elderly with increased pulse pressure. Indian Heart Journal 2017; 69(4):485-490. DOI:10.1016/j.ihj.2017.02.006
  31. Bagoji IG, Hadimani GA, Yendigeri SM,Das KK: Sub-chronic indomethacin treatment and its effect on the male reproductive system of albino rats: possible protective role of black tea extract. J Basic Clinical PhysiolPharmacol. 02/2017;  DOI:10.1515/jbcpp-2016-0168
  32. Das KK. No compromise to ethical research and publications. Indian J Health Sci Biomed Res 2017;10:1-2
  1. Das KK. Relevance of Vascular Sciences Research. J Krishna Inst Med Sci Univ 2017; 6(1): 1-2
  2. UgranV,Desai N, ChakrabortiD,MasaliKA,Mantur P, Kulkarni S,DeshmukhN,ChadchanKS,DasSN,Tanksali AS, ArwikarSP,Guggarigoudar SP, VallabhaT,Patil SS, Das KK. Groundwater fluoride contamination and its possible health implications in Indi taluk of Vijayapura District (Karnataka State), India..Environ Geochem Health.2017 Oct;39(5):1017-1029. DOI: 10.1007/s10653-016-9869-2 (4.609)
  3. Kori RS, Aldakatti RH, Desai SD, Das KK. Effect of Drug Alprazolam on RestrainedStress Induced Alteration of SerumCortisol and Antioxidant Vitamins (VitaminC and E) in Male Albino Rats. J ClinDiag Res 2016; 10(8): AF07-AF09. DOI: 10.7860/JCDR/2016/21355.8380
  4. Das KK, Nemegouda SR, Patil SG, Saha S. Possible Hypoxia Signaling Induced Alteration of Glucose Homeostasis in Rats Exposed to Chronic Intermittent Hypoxia – Role of Antioxidant (Vitamin C) and Ca2+ Channel Blocker (Cilnidipine)Current Signal Transduction Therapy 2016,11(1): 49-55
  5. Aithal M, Haseena S, Das KK Saheb SH. Effect of Nigella Sativa seed and Thymoquinone on Reproductive Parameters in Sterptozotocine Induced Diabetic and Normal Male Albino Rats. Int J Intg Med Sci 2016; 3 (3), 248-52
  6. Das KK,Vallabha T, Patil SM, Ray J, Deepak KK. Knowledge on Ethical Authorship: A Comparative Study Between Medical And Pharmacy Faculty. J Young Pharm 2016; 8(2);136-140. DOI:5530/jyp.2016.2.15
  7. Das KK, Razzaghi-Asl N.; Tikare SN, Di Santo R, Costi R; Messore A; Pescatori L; Crucitti GC; Jargar JG; Dhundasi SA; Saso L. Hypoglycemic activity of curcumin synthetic analogues inalloxan-induced diabetic rats. J Enzyme Inhib Med Chem 2016;31(1):99-105 (5.051)
  8. Patil PS, Aithal M, Pujari VM, Das KK.. Effect of occupational exposure on wbc count and oxidative stress in rice mill workers. J Krishna Inst Medical Sci Univ 2016; 5(1):27-31.
  9. Bagoji IB, Jargar JG, Yendigeri SM, Doshi MA, Patil BG, Das KK. Effect of supplementation of black tea extract on indomethacin inducedalteration of pathophysiology of rat liver.J Chem Pharm. Res 2015; 7(12):597-60
  10. Vallabha T, Karjol U, Kalyanappagol V, Sindigikar V, Nidoni R, Biradar H, Aniketan KV, Das KK. Rational Hyperoxia in the Perioperative Period: a Safe and Effective Tool in the Reduction of SSI. Indian J Surg 2016; 78(1):27-31. DOI 10.1007/s12262-015-1314-8 (1.01)
  11. Patil PS, Aithala M, Das KK. Effect of Occupational Exposure on Blood Cell Counts, Electrocardiogram and Blood Pressure in Rice Mill Workers. J ClinDiag Res 2015; 9(1):CC01-CC03.
  12. Patil SG, Aithala MR, Das KK. Effect of Yoga on Arterial Stiffness in Elderly Subjects with Increased Pulse Pressure: A Randomized Controlled Study. Complement Ther Med 2015.;23(4):562-9 (2.446)
  13. Das KK,Jargar JG, Saha S, Yendigeri SM, Singh SB. α – Tocopherol supplementation prevents lead acetate and hypoxia induced hepatic dysfunction. Indian J Pharmacol 2015; 47(3):285-291. (1.03)
  14. Haseena S, Aithala M, Das KK, SahebSH.Phytochemical Analysis of nigella sativaand its effect on reproductive system. J Pharm. Sci. & Res 2015; 7(8):514-517
  15. Desai SD,Saheb SH, Das KK, Haseena S. Effect of thymoquinone on MDA and SOD levels in streptozotocin induced diabetic albino rats. J Pharm. Sci. & Res 2015;7(8):523-526
  16. HaseenaS,Aithal M, Das KK, Saheb SH. Effect of nigella sativa seed powder on testosterone and LH levels in sterptozotocine induced diabetes male albino rats J Pharm. Sci. & Res 2015; 7(4):234-237
  17. Das KK.Journey of a researcher: From citation to ‘h-index. Int J ClinExpPhysiol 2015 ; 2 (1), 1
  18. Patil SG, Aithala M, Das KK. Evaluation of arterial stiffness in elderly with prehypertension. Indian J PhysiolPharmacol 2015; 59(1): 16-22
  19. Desai SD, Saheb SH, Das KK, . Effect of nigella sativa seed powder on MDA and SOD levels in sterptozotocine induced diabetes albino rats. J Pharm. Sci. & Res 2015; 7(4): 206-209
  20. Das KK, Saha S. Hypoxia, Lead Toxicities and Oxidative stress: Molecular interactions and antioxidant (Vitamin C) defense Current Signaling Transduction & Therapy 2014;9:113-122
  21. Jargar JG, Yendigeri S, Dhundasi SA, Das KK. Protective effect of Vitamin E (α-tocopherol) on nickel-induced alteration of testicular pathophysiology in alloxan treated diabetic rats. Int J ClinExpPhysiol 2014; I(4): 290-297
  22. Jargar JG, Dhundasi SA, Das KK. Influence of α-tocopherol on blood glucose regulation of alloxan induced male diabetic rats exposed to nickel sulfate. Biomedicine 2014; 34(3): 124-129 (068)
  23. Bagoji IB, Doshi MA, Yendegeri S, Patil BG ,Patil BB, Das KK. Black tea extracts ameliorates indomethacin induced changes in testicular histopathology of albino rats. J Young Pharmacists 2014; 6(3): 53-57.
  24. Qushnood F, Quadri SS, Dhundasi SA, Das KK. A study of stroke index and cardiac index in severe anemia. Int J Curr Res Acad Rev 2014 ; 2(2):71-78
  25. QushnoodF,Dhundasi SA, Das KK. Left ventricular functional changes in severe anemia by echo cardiography; A correlation study. J Evolution Med Dental Sci 2014;3(11):21-33
  26. Patil SG, Dhanakshirur GB, Aithala MR, Naregal G, Das KK. Effect of yoga on oxidative stress in elderly with grade I hypertension: A randomized control studies. J ClinDiagn Res 2014; 8(7): BC04-BC07.
  27. Mantur VS, Sommanavar MS, Yendegiri SM, Das KK,Goudar SS. Ameliorating effect of black tea extracts on cadmium chloride-induced alteration of serum lipid profile and liver histopathology in rats. Indian J PhysiolPharmacol 2014;58(2): 128-132
  28. Das KK. Physiology of today is the medicine of tomorrow: Is physiological science heading in the right direction?.Int.J.Clin.Exp.Physiol 2014; 1(1):82.
  29. Patil SG, Dhanakshirur G, Aithala MR, Das KK. Comparison of the effects of yoga and lifestyle modification on grade-I hypertension in elderly males: A preliminary study. Int J ClinExpPhysiol 2014; 1(1):68-72.
  30. Chadchan K, Das SN; Das Fenugreek (Trigonellafoenumgraecum) leaves extract and its interaction with heavy metal (Nickel II) with reference to glucose reduction capabilities in-vitro. Biomedicine 2014; 34(1):104-108.
  31. Mantur VS, Sommanavar MS, Goudar SS, Das KK. Protective role of Black Tea Extract on Cadmium Chloride (CdCl2) induced alteration of serum and liver nitric oxide and antioxidant vitamins(C & E) levels in male albino rats. Biomedicine 2014 ; 34(1):127-131.
  32. Hattiwale HM, Hattiwale SH, Dhundasi SA, Das KK.. Role of waiste to height ratio on percent recovery heart rate in young adult males of Bijapur, Karnataka (India).. Biomedicine 2013; 33(3):426-429.
  33. Das KK, Vallabha T, Ray J, Murthy PSN. Conflict of Interest -Serious Issue on Publication Ethics for Indian Medical Journals. J Nepal Med Asso 2013; 52(190):357-60.
  34. Tikare S, YendegiriSM ,DhundasiSA, Das KK. Protective effect of α-tocopherol against nickel sulfate induced hematotoxicity, hepatotoxicity and nephrotoxicity in male albino rats.. Indian J PhysiolPharmacol 2013; 57(03):280-292.
  35. Hattiwale SH, Saha S, Yendigeri SM, Jargar JG, Dhundasi SA, Das KK. Protective effect of L-ascorbic acid on nickel induced pulmonary nitrosative stress in male albino rats. Biometals 2013; 26(2), 329-336 (2.949)
  36. Aslam M, Siddiq M, Dhundasi SA, Kulkarni BR,Das KK. Short term memory status in depression patients of north Karnataka. J Evolution Med Dental Sci 2013; 2(3):290-296.
  37. Aslam M, Siddiq M, Dhundasi SA, Kulkarni BR, Das KK. Short-term Memory Status in Obsessive-Compulsive Disorder Patients of North Karnataka, India. Biomedicine 2013; 33(1):101-105.
  38. Das KK, Jargar JG, Hattiwale SH, Yendigeri SM, Das S, Dhundasi SA.  Serum Vitamin E (alpha-Tocopherol) Estimation. A Potential Biomarker of Antioxidant Status Evaluation on Heavy Metal Toxicities. Recent Patents on Biomarkers2013; 3:36-43.
  39. Chakraborti D, Rahman MM, Murrill M, Das R, Siddayya, Patil SG, Sarkar A, Dadapeer H J, Yendigeri SM, Ahmed R, Das KK.Environmental arsenic contamination and its health effects in a historic gold mining area of the Mangalur greenstone belt of Northeastern Karnataka, India.. J Hazard Mater 2013; 15; 262:1048-55 (10.588)
  40. Hattiwale HH, Hattiwale SH, Dhundasi SA, Das KK. Recovery Heart Rate Response in Sedentary and Physically Active Young Healthy Adults of Bijapur, Karnataka, India. Basic Sciences of Medicine 2012; 1(5):30-33.
  41. Tikare T, YendigeriSM , Gupta AD, Dhundasi SA, Das KK. Effect of garlic (Allium sativum) on hematology and erythrocyte antioxidant defense system of albino rats exposed to heavy metals (nickel II & chromium VI).. Indian J PhysiolPharmacol 2012; 56(2):137-46.
  42. ManiyarSA ,Jargar JG, Das SN, Dhundasi SA, Das KK. Alteration of chemical behavior of L-ascorbic acid in combination with nickel sulfate at different pH solutions in vitro.. Asian Pacific J Trop Biomed 2012; 2(3):220-2. ( IF.1.545)
  43. Jargar JG, Hattiwale SH, Das S, Dhundasi SA, Das KK. A modified simple method for determination of serum α-tocopherol (vitamin E). J Basic ClinPhysiolPharmacol 2012; 23(1):45-8.
  44. Jargar JG, Yendigeri SM, Hattiwale SH, Dhundasi SA, Das KK. α-Tocopherol ameliorates nickel induced testicular oxidative and nitrosative stress in albino rats. J Basic ClinPhysiolPharmacol 2012; 23(2):77-82.
  45. Hattiwale HM, Hattiwale SH, Das KK, Dhundasi SA. Rate Pressure Product and Pressure Rate Quotient in Severe Anemic Women of North Karnataka. Biomedicine 2012; 32(3):410-413.
  46. Das KK.The editorial policy on conflict of interest- A major issue for the Indian medical journals. J Krishna Inst Med Sci Univ 2012;1{1}:4-5
  47. Aslam M, Siddiq M, Dhundasi SA, Das KK, Kulkarni BR. Study of short term memory status in adult bipolar disorder patients in south Indian population.. Indian J PhysiolPharmacol 2011, 55(2):160-4.
  48. Das KK, Dhundasi SA, Das SN. Hexavalent chromium and its effect on health: possible protective role of garlic (Allium sativum Linn).. J Basic ClinPhysiolPharmacol 2011; 22(1-2):3-10.
  49. Parkar MA, Ahmed R, Abdullah BB, Patil BS, DasEffect of cell phone exposure on physiologic and hematologic parameters of male medical students of Bijapur (Karnataka) with reference to serum lipid profile. J Basic ClinPhysiolPharmacol 2010; 21(2):201-10.
  50. Das KK, Saha S. L-ascorbic acid and α tocopherol supplementation and antioxidant status in nickel- or lead-exposed rat brain tissue. J Basic ClinPhysiolPharmacol 2010; 21(4):325-46.
  51. Das KK.A Comprehensive Review on Nickel (II) And Chromium VI Toxicities – Possible Antioxidant (Allium Sativum Linn) Defenses. Al Ameen J Med Sci 2009; 2(2):43-50.
  52. Das KK, Dundasi SA.A Brief Review on Health Risk Assessment of Nickel, Hexavalent Chromium and Lead – Role of Heavy Metals in Cellular Hypoxia. Indian J Med Biochem 2009; 13(2):3-9.
  53. Rishad A, Patil BS, Das KK. Relevance of Adenosine Deaminase as a Marker For Tuberculous Pleural Effusion in Developing Countries. Asian Pacific J Trop Med 2009; 2(2):45-48.( 1.226)
  54. Das KK:,Gupta AD, Dhara PC, Dhundasi S. Effect of garlic (Allium sativum) on nickel II or chromium VI induced alterations of glucose homeostasis and hepatic antioxidant status under sub-chronic exposure conditions.. J Basic ClinPhysiolPharmacol 2009; 20(1):1-14.
  55. Chavan NR, Dhundasi SA, Das KK. Determination of sensitivity among various cardiovascular autonomic function tests in diabetic patients of Bijapur. J Basic ClinPhysiolPharmacol2009 ; 20(2):187-96.
  56. Das KK. Effect of garlic (allium sativum) on nickel II and chromium VI toxicities in normal and alloxan induced diabetic rats.. J PhysiolSci  2009; 59:331. (4.33)
  57. Das KK, Das SN, Dhundasi SA. Nickel, its adverse health effects & oxidative stress.. Indian J Med Res 2008; 128(4):412-25. (2.375)
  58. Das KK.Elemental speciation in human health risk assessment. Indian J Med Res 2008; 127(10):417-420. (2.375)
  59. Gupta AD, Das SN, Dhundasi SA, Das KK. Effect of garlic (Allium sativum) on heavy metal (nickel II and chromium VI) induced alteration of serum lipid profile in male albino rats..Int J Environ Res Public Health 2008; 5(3):147-51. (3.390)
  60. Tikare SN, Das KK, Dhundasi SA. Blood leukocyte profile in different phases of menstrual cycle.. Indian J PhysiolPharmacol 2008; 52(2):201-4.
  61. Tikare SN, Gupta AD, Dhundasi SA, Das KK. Effect of antioxidants L-ascorbic acid and alpha-tocopherol supplementation in nickel exposed hyperglycemic rats. J Basic ClinPhysiolPharmacol 2008; 19(2):89-101.
  62. Gupta AD, Dhundasi SA, Dhara PC, Das KK. Influence of α-tocopherol on nickel induced alteration of serum lipid profile in male albino rats.. Asian Pacific J Trop Med 2008; 1(1):14-18. (1.77)
  63. Hattiwale HM, Hattiwale SH, Das KK, Dhundasi:SA. Rate Pressure Product and Pressure Rate Quotient in Severe Anemic Women of North Karnataka. Biomedicine 2008; 32(3):410-413.
  64. Ahmed R, Sufiyan M, Athar AM, Patil BS,Das KK. Influence of diurnal variation of arterial blood pressure on age-matched normotensive and essential hypertensive subjects. Biomedicine 2008; 28(1):54
  65. Hattiwale HM, Maniyar SA, Das KK, Dhundasi SA. Role of body mass index on physical fitness index in two different age groups of healthy young males from north interior Karnataka, India. Al Ameen J Med Sci 2008; 1(1):50-54.
  66. Maniyar SA, Hattiwale HM, Das KK, Dhundasi SA. A study to evaluate the differences in the effect of right and left carotid sinus massage on young healthy adult male and female subjects. Biomedicine; 28 (4): 305-309.. Biomedicine 2008; 28(4):305-309
  67. Das KK, Gupta AD, Dhundasi SA, Patil AM, Das SN, Ambekar JG. Protective role of L-ascorbic acid on antioxidant defense system in erythrocytes of albino rats exposed to nickel sulfate..Biometals 2007; 20(2):177-84. (2.949)
  • Gupta AD, Dhundasi SA, Ambekar JG, DasKK. Effect of l-ascorbic acid on antioxidant defense system in testes of albino rats exposed to nickel sulfate.. J Basic ClinPhysiolPharmacol 2007; 18(4):255-66.
  • Patil AJ, Bhagwat VR, PatilJA,Dongre NA, Ambekar JG, Das KK.. Occupational Lead exposure in Battery Manufacturing Workers, Silver Jewellery Workers and Spray Painters in Western Maharashtra (India): Effect on Liver and Kidney functions.. J Basic ClinPhysiolPharmacol 2007; 18(02):87-100.
  • Tikare SN, Das KK, Sinha P, Dhundasi SA. Influence of different phases of menstrual cycle on platelets. Biomedicine 2007; 27 (4): 173-175
  • Das KK, Buchner V. Effect of nickel exposure on peripheral tissues: role of oxidative stress in toxicity and possible protection by ascorbic acid.. Reviews Environ Health 2007; 22(2):157-73 (IF:448)
  • Patil AJ, Bhagwat VR, Patil JA, Dongre NN, Ambekar JG, Das KK. Biochemical Aspects of Lead Exposure and Toxicity in Spray Painters of Western Maharashtra(India). J Environ Health Res 2007; 6(2):101-110.
  • Patil AJ, Bhagwat VR, PatilJA,Dongre NN, Ambekar JG, Jailkhani R, Das KK. Effect of lead (Pb) exposure on the activity of superoxide dismutase and catalase in battery manufacturing workers (BMW) of Western Maharashtra (India) with reference to heme biosynthesis Int J Environ Res Public Health 2006; 3(4):329-37 (3.390)
  • Das KK, Gupta AD, Dhundasi SA, Patil AM, Das SN, Ambekar JG. Effect of L-ascorbic acid on nickel-induced alterations in serum lipid profiles and liver histopathology in rats. J Basic ClinPhysiolPharmacol 2006; 17(1):29-44.
  • Gupta AD, Patil AM, Ambekar JG, Das SN, Dhundasi, SA, Das KK. L-ascorbic acid protects the antioxidant defense system in nickel-exposed albino rat lung tissue. J Basic ClinPhysiolPharmacol 2006; 17(2):87-100.
  • Patil AJ, Bhagwat VR, Patil JA, Dongre NN, Ambekar JG, Das KK. Biochemical aspects of lead exposure in silver jewelry workers in western Maharashtra (India). J Basic ClinPhysiolPharmacol 2006; 17(4):213-29.
  • Das KK, Das SN. Studies on the role of ascorbic acid on nickel induced hepatic nucleic acid concentrations in rats. J Basic ClinPhysiolPharmacol 2004; 15(3-4):185-95.
  • Das KK, Dasgupta S. Effect of nickel sulfate on testicular steroidogenesis in rats during protein restriction.. Environ Health Perspect 2002; 110(9):923-6.(9.031)
  • Das KK, Dhundasi SA. A study on predictors of Peak Expiratory Flow Rate in Muslim subjects (aged 18 to 20 years) of Karnataka.. Indian J PhysiolPharmacol 2002; 46(3):321-7.
  • Das KK, Dhundasi SA. Physical fitness: a longitudinal study among Muslim children of Bijapur (Karnataka). Indian J PhysiolPharmacol 2001; 45(4):457-62.
  • Das KK, Das SN, Dasgupta S. The influence of ascorbic acid on nickel-induced hepatic lipid peroxidation in rats.. J Basic ClinPhysiolPharmacol 2001; 12(3):187-95.
  • Das KK, Dasgupta S. Effect of nickel on testicular nucleic acid concentrations of rats on protein restriction..Biol Trace Elem Res 2000; 73(2):175-80.(IF.3.738)
  • Das KK, Choudhui S, Biswas NM. Role of Ascorbic Acid on Transaminase Activities in some Metabolically Active Tissues of Aspirin Treated Rats. Indian J PhysiolPharmacol 1999; 43(1):70-72.
  • Das KK,Dasgupta S. Studies on the role of nickel in the metabolism of ascorbic acid and cholesterol in experimental animal. Ind J  Physiol& Allied Sci 1998 ; 52:58-62
  • Das, KK, Dasgupta S: Alteration of testicular biochemistry during protein restriction in nickel treated rats..Biol Trace Element Res1997; 60(3):243-9. (3.738)
  • Das KK, DasguptaS.. Influence of ascorbic acid on acid and alkaline phosphatase activities in some metabolically active tissues of aspirin treated rats.. Indian J PhysiolPharmacol 1997; 41(4):421-3
  • Das KK, Dasguta S, Biswas SK. Effect of nickel on acid and alkaline phosphate activities in the reproductive system of male rats during proteins restriction. Medical Science Research. 1996; 17:85-89
CONTRIBUTION TO NATIONAL/INTERNATIONAL ISSUES:
  1. My team’s research was the first among the researchers in the world to report chronic human arsenic toxicity in any historic gold mining area (J Hazard Mater 2013Nov 15;262:1048-55).
  2. Being a person with a disability I work for disability issues with various NGOs.
  3. At present, I am working as a member of the Education Committee of the International Union of Physiological Sciences (IUPS), USA for the period from Jan 2015 to December 2018 and 2018 to 2022.
  4. I am also holding the position of President of the South Asian Association of Physiologists. The University of Colombo, Sri Lanka (2020-2022)
  5. I am also actively involved in the cause of Ethical Publication and am the Permanent Member of the Committee on Publication Ethics (COPE), United Kingdom. Further, I was also the first Indian to be awarded “COPE International Scholarship” in 2012 to present his works on ethical publications in London
AFFILIATION TO SCIENTIFIC/TECHNICAL COMMITTEES AT STATE/NATIONAL/INTERNATIONAL LEVEL:
  1. Chairman, Committee for Promotion of Science, Humanities and Research (CPSHR), BLDE Association, Vijayapur ( 2021- )
  2. Chairman, Doctoral Committee, BLDE ( Deemed to be University, Vijayapur (2021-)
  3. Dean of Environmental Health, UNESCO Chair-Life Sciences (Biophysics, Biotechnology & Environmental Health), Life Sciences International Postgraduate Educational Center(2018-2022)
  4. External Member (Postgraduate Preclinical) -Rajiv Gandhi University of Health Sciences, Karnataka, Government of Karnataka (2015-2018)
  5. External Member Ph.D. Review Committee, PIMS Deemed University, Loni, Maharashtra
  6. External Member – Ph.D. Registration Committee, Rajiv Gandhi University of Health Sciences, Government of Karnataka (2015-2018)
  7. Research Adviser- BLDE (Deemed to be University), Vijayapur ( 2018-2021)
  8. Research Adviser- Krishna Institute of Medical Sciences University, Karad, Maharashtra (2015-)
  9. Research Advisor- BLDEA’s Dr.P.G.Halakatti College of Engineering & Technology, Vijayapur (2018-2020)
  10. Member-International Advisory Group, Committee on Publication Ethics, UK (2013-2015).
AWARDS & HONORS:
  1. Honorary Fellow, KSTA, DST, Government of Karnataka
  2. ISCA Endowment Lecture and G.P.Chatterjee Memorial Award 2019 by Indian Science Congress Association, DST, Ministry of Sc.& Tech, Government of India on January 3, 2019
  3. Silver Jubilee Oration- March 6, 2018, KIMS Deemed University, Karad
  4. Fellow of Royal Society of Biology- January 1, 2018, by Royal Society of Biology, UK
  5. Jajneswar Chakraborty Memorial Orationby Bengal Obstr&Gynecol Society, Kolkata on 8th July 2017
  6. Science, Honor & Truth Medalby High Altitude Pulmonary and Pathology Institute, Zubieta University, La Paz, Bolivia on 8th Oct 2016
  7. N.Chaudary Memorial Research Prize by Association of Physiologists of India (JIPMER) on 15th Sep 2016
  8. Raja Ramanna State Scientist Award by Ministry of Science & Technology, Government of Karnataka on 30th Dec 2015.
  9. MCRC- Distinguished Lecture 2015by Multidisciplinary Cardiovascular Research Centre, the University of Leeds on 31st.July 2015.
  10. Shri Dev Raj Bajaj Research Prize by Association of Physiologists and Pharmacologists of India (2014)
  11. Best Researcher Award -2014 by BLDE University at 2nd University convocation (2014).
  12. C.R.Krishnamurthy Memorial Oration Award by The Indian Association of Biomedical Scientists, India-(2012).
  13. S.R. Maitra Memorial Oration Award by The Physiological Society of India (2011)
  14. ShakuntalaDasgupta Memorial Oration Award by The Physiological Society of India (2003)
INTERNATIONAL SCHOLARSHIPS:
  1. MCRC-Research Lecture” by Multidisciplinary Cardiovascular Research Centre, University of

Leeds on 31st.July 2015

  1. Awarded ‘The Physiological Society-UK Scholarship 2012’ to deliver a lecture at the University of Edinburgh, Edinburgh, UK. During July-August, 2012
  2. Awarded “COPE International Scholarship-2012” by Committee on Publication, during March 2012. 1st Indian Medical Journal Editor to receive this award
EMR PROJECT COMPLETED: 08

Ongoing: 01: VGST-K FIST (Level 2), (DST, Government of Karnataka (2016-2019). “Effect of L-ascorbic acid and calcium channel blocker on hypoxia exposed possible alteration of cell signaling pathways in the respiratory system of male rats with or without heavy metal lead exposure” (VGST-KFIST/1230/2015-16 dated 22/6/2016.(Rs.40,00,000/-)

PROJECT ASSESSORS:
  1. DST (Govt. of India)
  2. ICMR (Ministry of Health, Govt. of India)
  1. DRDO (Ministry of Defence, Government of India)
  2. National Science Council, Poland
List of Publications :